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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Integrin alpha-1
Summary
- UniProt ID
- P56199
- Gene Symbol
-
- ITGA1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell adhesion
- Disulfide bond
- Glycoprotein
- Integrin
- Magnesium
- Metal-binding
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| cell surface |
| plasma membrane |
| membrane |
| acrosomal vesicle |
| perikaryon |
| basal part of cell |
| integrin alpha1-beta1 complex |
| focal adhesion |
| integrin complex |
| GO Term |
|---|
| metal ion binding |
| integrin binding |
| collagen binding |
| protein phosphatase binding |
| collagen binding involved in cell-matrix adhesion |
Sequence
MAPRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 426 |
|
|||
| 460 | N-linked (GlcNAc...) asparagine | |||
| 532 | N-linked (GlcNAc...) asparagine | |||
| 699 | N-linked (GlcNAc...) asparagine |
|
||
| 748 | N-linked (GlcNAc...) asparagine |
|
||
| 780 | N-linked (GlcNAc...) asparagine | |||
| 840 | N-linked (GlcNAc...) asparagine | |||
| 883 | N-linked (GlcNAc...) asparagine | |||
| 908 | N-linked (GlcNAc...) asparagine |
|
||
| 915 | N-linked (GlcNAc...) asparagine |
|
G49108TO
G15664MX
G83460ZZ
G10488MI
G72747WU
G70619PT
G46503DX
G70101JE
G80920RR
G90659AW
G62765YT
G64527OM
G31852PQ
G41247ZX
G02815KT
G92050GC
G45395BF
G14972EH
G00912UN
G87661QW
G76295SF
G04657PL
G27058EU
G41071NU
G07755XJ
G86182NS
G59626AS
G25079LO
G65184UU
G42124LM
G59924QI
G47644PP
G72790NZ
G10486CT
G05049YU
G28541PG
G18647XP
G85269DF
G95865ZB
G39446WN
G11314AS
G57776ZU
G01650EU
G02886BB
G37399XV
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CHL1 interactions | Homo sapiens |
| Integrin cell surface interactions | Homo sapiens |
| Laminin interactions | Homo sapiens |
| Other semaphorin interactions | Homo sapiens |
| Platelet Adhesion to exposed collagen | Homo sapiens |
| Smooth Muscle Contraction | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
