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Histone deacetylase 4
Summary
- UniProt ID
- P56524
- Gene Symbol
-
- HDAC4
- KIAA0288
- Gene ID
- 9759
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Chromatin regulator
- Coiled coil
- Cytoplasm
- Disease variant
- Epilepsy
- Hydrolase
- Intellectual disability
- Isopeptide bond
- Metal-binding
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repressor
- Transcription regulation
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| nuclear speck |
| chromatin |
| nucleus |
| cytoplasm |
| nucleoplasm |
| cytosol |
| histone deacetylase complex |
| transcription repressor complex |
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | Homo sapiens |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | Homo sapiens |
| NOTCH1 Intracellular Domain Regulates Transcription | Homo sapiens |
| Notch-HLH transcription pathway | Homo sapiens |
| RUNX2 regulates chondrocyte maturation | Homo sapiens |
| RUNX3 regulates p14-ARF | Homo sapiens |
| SUMOylation of chromatin organization proteins | Homo sapiens |
| SUMOylation of intracellular receptors | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12704 | ataxia telangiectasia | |
| DOID:8466 | retinal degeneration | |
| DOID:8670 | eating disorder |
