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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pro-neuregulin-2, membrane-bound isoform
Summary
- UniProt ID
- P56974
- Gene Symbol
-
- Nrg2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Growth factor
- Immunoglobulin domain
- Reference proteome
- Secreted
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| plasma membrane |
| glutamatergic synapse |
| GABA-ergic synapse |
Sequence
MRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPLVFKTAFAPVDPNGKNIKKEVGKILCTDCATRPKLKKMKSQTGEVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVRVEDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPVGYTGDRCQQFAMVNFSKHLGFELKEAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRRQMHHHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRREAETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSQEERRRAAMPPYHDSIDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGSGPGADMQRSYDSYYYPAAGPGPRRSACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRTRGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGCGSASASDDDADDADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPTRAKQDSGPL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 55 | N-linked (GlcNAc...) asparagine | |||
| 186 | N-linked (GlcNAc...) asparagine | |||
| 254 | N-linked (GlcNAc...) asparagine | |||
| 296 | N-linked (GlcNAc...) asparagine |
|
G86182NS
G42124LM
G05724UK
G39446WN
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| RAF/MAP kinase cascade | Mus musculus |
| SHC1 events in ERBB2 signaling | Mus musculus |
| SHC1 events in ERBB4 signaling | Mus musculus |
| Signaling by ERBB2 | Mus musculus |
| Signaling by ERBB4 | Mus musculus |
