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Forkhead box protein L2

Summary

UniProt ID

P58012

Gene Symbol

FOXL2

Gene ID

668

Organism

Homo sapiens (human)

External Links

GlyGen: P58012
PubChem: P58012
The O-GlcNAc Database: P58012
Re-Glyco: P58012

Annotation

Keyword

3D-structure
DNA-binding
Differentiation
Disease variant
Isopeptide bond
Nucleus
Phosphoprotein
Premature ovarian failure
Reference proteome
Transcription regulation
Triplet repeat expansion
Ubl conjugation

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
chromatin
nucleus
Flemming body
nucleoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 19 in total

1

2

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GO Term
single fertilization
anatomical structure morphogenesis
cell differentiation
positive regulation of luteinizing hormone secretion
positive regulation of apoptotic process
positive regulation of DNA-templated transcription
oocyte growth
positive regulation of follicle-stimulating hormone secretion
embryonic eye morphogenesis
negative regulation of transcription by RNA polymerase II

Displaying **all 9** entries
GO Term
sequence-specific double-stranded DNA binding
cysteine-type endopeptidase regulator activity involved in apoptotic process
ubiquitin conjugating enzyme binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
DNA-binding transcription factor activity
nuclear estrogen receptor binding

Annotation information from UniProt.

Sequence

MMASYPEPEDAAGALLAPETGRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
44		GlyGen
263	G49108TO	The O-GlcNAc Database
338		GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
SUMOylation of transcription factors	Homo sapiens

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080860	primary ovarian insufficiency 3	Alliance of Genome Resources
DOID:14778	blepharophimosis, ptosis, and epicanthus inversus syndrome	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources