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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Toll-like receptor 7
Summary
- UniProt ID
- P58681
- Gene Symbol
-
- Tlr7
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003723
- PubChem
- P58681
- RaftProt
- P58681
Annotation
- Keyword
-
- Cytoplasmic vesicle
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- Lysosome
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| response to cGMP |
| GO Term |
|---|
| lysosome |
| plasma membrane |
| receptor complex |
| early phagosome |
| endosome |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| endosome membrane |
| GO Term |
|---|
| pattern recognition receptor activity |
| double-stranded RNA binding |
| single-stranded RNA binding |
| siRNA binding |
Sequence
MVFSMWTRKRQILIFLNMLLVSRVFGFRWFPKTLPCEVKVNIPEAHVIVDCTDKHLTEIPEGIPTNTTNLTLTINHIPSISPDSFRRLNHLEEIDLRCNCVPVLLGSKANVCTKRLQIRPGSFSGLSDLKALYLDGNQLLEIPQDLPSSLHLLSLEANNIFSITKENLTELVNIETLYLGQNCYYRNPCNVSYSIEKDAFLVMRNLKVLSLKDNNVTAVPTTLPPNLLELYLYNNIIKKIQENDFNNLNELQVLDLSGNCPRCYNVPYPCTPCENNSPLQIHDNAFNSLTELKVLRLHSNSLQHVPPTWFKNMRNLQELDLSQNYLAREIEEAKFLHFLPNLVELDFSFNYELQVYHASITLPHSLSSLENLKILRVKGYVFKELKNSSLSVLHKLPRLEVLDLGTNFIKIADLNIFKHFENLKLIDLSVNKISPSEESREVGFCPNAQTSVDRHGPQVLEALHYFRYDEYARSCRFKNKEPPSFLPLNADCHIYGQTLDLSRNNIFFIKPSDFQHLSFLKCLNLSGNTIGQTLNGSELWPLRELRYLDFSNNRLDLLYSTAFEELQSLEVLDLSSNSHYFQAEGITHMLNFTKKLRLLDKLMMNDNDISTSASRTMESDSLRILEFRGNHLDVLWRAGDNRYLDFFKNLFNLEVLDISRNSLNSLPPEVFEGMPPNLKNLSLAKNGLKSFFWDRLQLLKHLEILDLSHNQLTKVPERLANCSKSLTTLILKHNQIRQLTKYFLEDALQLRYLDISSNKIQVIQKTSFPENVLNNLEMLVLHHNRFLCNCDAVWFVWWVNHTDVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSVSISSVLFLMVVMTTSHLFFWDMWYIYYFWKAKIKGYQHLQSMESCYDAFIVYDTKNSAVTEWVLQELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTQKYAKTESFKMAFYLSHQRLLDEKVDVIILIFLEKPLQKSKFLQLRKRLCRSSVLEWPANPQAHPYFWQCLKNALTTDNHVAYSQMFKETV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 66 | N-linked (GlcNAc...) asparagine |
|
||
| 69 | N-linked (GlcNAc...) asparagine |
|
||
| 167 | N-linked (GlcNAc...) asparagine |
|
||
| 190 | N-linked (GlcNAc...) asparagine |
|
||
| 215 | N-linked (GlcNAc...) asparagine |
|
||
| 387 | N-linked (GlcNAc...) asparagine |
|
||
| 524 | N-linked (GlcNAc...) asparagine |
|
||
| 535 | N-linked (GlcNAc...) asparagine |
|
||
| 591 | N-linked (GlcNAc...) asparagine |
|
||
| 680 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of TLR by endogenous ligand | Mus musculus |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | Mus musculus |
| Trafficking and processing of endosomal TLR | Mus musculus |
