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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Spike glycoprotein
Summary
- UniProt ID
- P59594
- Gene Symbol
-
- S
- Organism
- Severe acute respiratory syndrome-related coronavirus
Annotation
- Keyword
-
- 3D-structure
- Coiled coil
- Disulfide bond
- Fusion of virus membrane with host endosomal membrane
- Glycoprotein
- Host cell membrane
- Inhibition of host tetherin by virus
- Palmitate
- Reference proteome
- Signal
- Transmembrane helix
- Viral attachment to host cell
- Viral envelope protein
- Virulence
- Gene Ontology (GO)
| GO Term |
|---|
| membrane |
| virion membrane |
| viral envelope |
| host cell plasma membrane |
| host cell endoplasmic reticulum-Golgi intermediate compartment membrane |
| GO Term |
|---|
| identical protein binding |
| host cell surface receptor binding |
Sequence
MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEGKAYFPREGVFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 29 | N-linked (GlcNAc...) asparagine; by host |
|
||
| 65 | N-linked (GlcNAc...) asparagine; by host | |||
| 73 | N-linked (GlcNAc...) asparagine; by host | |||
| 109 | N-linked (GlcNAc...) asparagine; by host |
|
||
| 118 | N-linked (GlcNAc...) asparagine; by host |
|
||
| 119 | N-linked (GlcNAc...) asparagine; by host |
|
||
| 158 | N-linked (GlcNAc...) asparagine; by host | |||
| 214 |
|
|||
| 227 | N-linked (GlcNAc...) asparagine; by host | |||
| 269 | N-linked (GlcNAc...) asparagine; by host |
G80920RR
G62765YT
G31852PQ
G41247ZX
G02815KT
G92050GC
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Attachment and Entry | Homo sapiens |
| Maturation of spike protein | Homo sapiens |
| SARS-CoV-1 activates/modulates innate immune responses | Homo sapiens |
| Translation of Structural Proteins | Homo sapiens |
| Virion Assembly and Release | Homo sapiens |
