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Standards Ontologies Notations
Spike glycoprotein

Summary
UniProt ID
P59594
Gene Symbol
  • S
Organism
Severe acute respiratory syndrome-related coronavirus
GlyConnect
GlyGen
P59594
PubChem
P59594
Annotation
Keyword
  • 3D-structure
  • Coiled coil
  • Disulfide bond
  • Fusion of virus membrane with host endosomal membrane
  • Glycoprotein
  • Host cell membrane
  • Inhibition of host tetherin by virus
  • Palmitate
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Viral attachment to host cell
  • Viral envelope protein
  • Virulence
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEGKAYFPREGVFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 11 - 20 of 26 in total
Position Description PubMed ID GlyTouCan ID Source
269 N-linked (GlcNAc...) asparagine; by host
318 N-linked (GlcNAc...) asparagine; by host
330 N-linked (GlcNAc...) asparagine; by host
357 N-linked (GlcNAc...) asparagine; by host
589 N-linked (GlcNAc...) asparagine; by host
602 N-linked (GlcNAc...) asparagine; by host
691 N-linked (GlcNAc...) asparagine; by host
699 N-linked (GlcNAc...) asparagine; by host
783 N-linked (GlcNAc...) asparagine; by host
1056 N-linked (GlcNAc...) asparagine; by host
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
Attachment and Entry Homo sapiens
Maturation of spike protein Homo sapiens
SARS-CoV-1 activates/modulates innate immune responses Homo sapiens
Translation of Structural Proteins Homo sapiens
Virion Assembly and Release Homo sapiens
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024