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14-3-3 protein epsilon

Summary

UniProt ID

P62259

Gene Symbol

Ywhae

Gene ID

22627

Organism

Mus musculus (house mouse)

External Links

GlyGen: P62259
PubChem: P62259
RaftProt: P62259
Re-Glyco: P62259

Annotation

Keyword

Acetylation
Cytoplasm
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
nucleus
cytoplasm
mitochondrion
plasma membrane
melanosome
endoplasmic reticulum
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 19 in total

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GO Term
protein localization to nucleus
cellular response to heat
positive regulation of hippo signaling
regulation of cytosolic calcium ion concentration
protein localization to endoplasmic reticulum
cytoplasmic pattern recognition receptor signaling pathway
negative regulation of toll-like receptor signaling pathway
negative regulation of protein dephosphorylation
positive regulation of protein export from nucleus
regulation of potassium ion transmembrane transporter activity

Displaying entries **1 - 10** of 13 in total

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GO Term
ubiquitin protein ligase binding
signaling adaptor activity
identical protein binding
histone deacetylase binding
transmembrane transporter binding
protein heterodimerization activity
phosphoserine residue binding
scaffold protein binding
protein sequestering activity
calcium channel inhibitor activity

Annotation information from UniProt.

Sequence

MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQDVEDENQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
227			G49642SA	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 16 in total

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Pathway Name	Organism
AURKA Activation by TPX2	Mus musculus
Activation of BAD and translocation to mitochondria	Mus musculus
Anchoring of the basal body to the plasma membrane	Mus musculus
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	Mus musculus
HSF1 activation	Mus musculus
Loss of Nlp from mitotic centrosomes	Mus musculus
Loss of proteins required for interphase microtubule organization from the centrosome	Mus musculus
NADE modulates death signalling	Mus musculus
RAB GEFs exchange GTP for GDP on RABs	Mus musculus
RHO GTPases activate PKNs	Mus musculus

Disease

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060469	Miller-Dieker lissencephaly syndrome	Alliance of Genome Resources
DOID:0060480	left ventricular noncompaction	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements