RAB GEFs exchange GTP for GDP on RABs

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GGC-RAB1:GDP:GDIs,CHMsGGC-RAB1:GTPGTPGDIs,CHMsGDPGGC-RAB3A:GTPGGC-RAB3A:GDP:GDIs,CHMsGGC-RAB5:GTPGGC-RAB5:GDP:GDIs,CHMsGGC-RAB6:GDP:GDIs,CHMsGGC-RAB6:GTPGGC-RAB7:GTPGGC-RAB7:GDP:GDIs,CHMsGGC-RAB8:GDP:GDIs,CHMsGGC-RAB8:GTPGGC-RAB9:GDP:GDIs,CHMsGGC-RAB9:GTPGGC-RAB10:GDP:GDIs,CHMsGGC-RAB10:GTPDennd3A2RT67ATPADPGGC-RAB12:GTPGCC-RAB12:GDP:GDIs,CHMsGGC-RAB13:GDP:GDIs,CHMsGGC-RAB13:GTPGGC-RAB14:GDP:GDIs,CHMsGGC-RAB14:GTPGGC-RAB21:GDP:GDIs,CHMsGGC-RAB21:GTPGGC-RAB27:GDP:GDIs,CHMsRAB27:GTPGGC-RAB31:GDP:GDIs,CHMsGGC-RAB31:GTPp-2S DENND1A, DENND1BDENND1A, DENND1B14-3-3 epsilon dimerp-2S-DENND1A,B:YWHAE dimerGGC-RAB35:GDP:GDIs,CHMsGGC-RAB35:GTPRAB32,RAB38:GDP:GDIs,CHMsRAB32,RAB38:GTPGGC-RAB39:GTPGGC-RAB39:GDP:GDIs,CHMsGGC-RAB18:GDP:GDIs,CHMsGGC-RAB18:GTP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025