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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hemoglobin subunit beta
Summary
- UniProt ID
- P68871
- Gene Symbol
-
- HBB
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Congenital dyserythropoietic anemia
- Direct protein sequencing
- Disease variant
- Glycation
- Heme
- Hypotensive agent
- Oxygen transport
- Phosphoprotein
- Pyruvate
- Reference proteome
- S-nitrosylation
- Vasoactive
- Gene Ontology (GO)
| GO Term |
|---|
| oxygen carrier activity |
| oxygen binding |
| heme binding |
| hemoglobin binding |
| hemoglobin alpha binding |
| organic acid binding |
| metal ion binding |
Sequence
MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 2 | N-linked (Glc) (glycation) valine; in Hb A1c |
|
||
| 9 | N-linked (Glc) (glycation) lysine |
|
||
| 18 | N-linked (Glc) (glycation) lysine |
|
||
| 45 |
|
|||
| 50 |
|
|||
| 67 | N-linked (Glc) (glycation) lysine |
|
||
| 73 |
|
|||
| 85 |
|
|||
| 121 | N-linked (Glc) (glycation) lysine |
|
||
| 145 | N-linked (Glc) (glycation) lysine; alternate |
|
G27391WQ
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Chaperone Mediated Autophagy | Homo sapiens |
| Cytoprotection by HMOX1 | Homo sapiens |
| Erythrocytes take up carbon dioxide and release oxygen | Homo sapiens |
| Erythrocytes take up oxygen and release carbon dioxide | Homo sapiens |
| Factors involved in megakaryocyte development and platelet production | Homo sapiens |
| Heme signaling | Homo sapiens |
| Late endosomal microautophagy | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| Scavenging of heme from plasma | Homo sapiens |
