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Serine/threonine-protein kinase N1

Summary

UniProt ID

P70268

Gene Symbol

Pkn1
Pkn
Prk1
Prkcl1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P70268
PubChem: P70268

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Cell membrane
Chromatin regulator
Coiled coil
Cytoplasm
Endosome
Nucleus
Phosphoprotein
Reference proteome
Repeat
Serine/threonine-protein kinase
Transcription regulation

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

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GO Term
B cell homeostasis
B cell apoptotic process
negative regulation of protein phosphorylation
regulation of germinal center formation
regulation of immunoglobulin production
renal system process
epithelial cell migration
phosphorylation
hyperosmotic response
negative regulation of B cell proliferation

Displaying **all 7** entries
GO Term
cytoplasmic vesicle
protein-containing complex
midbody
endosome
cleavage furrow
nucleus
cytoplasm

Displaying entries **1 - 10** of 13 in total

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GO Term
nuclear androgen receptor binding
nuclear receptor coactivator activity
diacylglycerol-dependent serine/threonine kinase activity
protein kinase C binding
ATP binding
small GTPase binding
histone H3T11 kinase activity
histone binding
histone deacetylase binding
protein serine kinase activity

Annotation information from UniProt.

Sequence

MAGDAVQSEPRSWSLLEQLGLAGADLAAPGVQQQLELERERLKREIRKELKLKEGAENLRRATTDLGRSLAPVELLLRGSARRLDLLHQQLQELHAHVVLPDPAAGSDATQSLAEGSPICSSTNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSSKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQALQAGELESQAAPDEAQGDPELGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSGAKAPDRKAVSEAQEKLTESNQKLGLLRESLERRLGELPADHPKGRLLREELTAASSSAFSAILPGPFPATHYSTLSKPAPLTGTLEVRVVGCKNLPETIPWSPPPSVGASGTPESRTPFLSRPARGLYSRSGSLSGRSSLRGEAENATEVSTVLKLDNTVVGQTAWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPIIERIPRLQRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPSAVATGTFSPNASPGAEIRHTGDISMEKLNLGADSDSSSQKSPPGLPSTSCSLSSPTHESTTSPELPSETQETPGPGLCSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFRDFDFVAGGY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
154			G02815KT	GlyGen
			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	Mus musculus
RAC1 GTPase cycle	Mus musculus
RHO GTPases activate PKNs	Mus musculus
RHOA GTPase cycle	Mus musculus
RHOB GTPase cycle	Mus musculus
RHOC GTPase cycle	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements