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MIRAGE
Runt-related transcription factor 1
Summary
- UniProt ID
- Q01196
- Gene Symbol
-
- AML1
- CBFA2
- RUNX1
- Gene ID
- 861
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative splicing
- Chloride
- Chromosomal rearrangement
- DNA-binding
- Disease variant
- Methylation
- Nucleus
- Phosphoprotein
- Proteomics identification
- Proto-oncogene
- Reference proteome
- Repressor
- Transcription regulation
- Gene Ontology (GO)
| GO Term |
|---|
| core-binding factor complex |
| chromatin |
| nucleus |
| intracellular membrane-bounded organelle |
| nucleoplasm |
| GO Term |
|---|
| chondrocyte differentiation |
| regulation of transcription by RNA polymerase II |
| neuron differentiation |
| positive regulation of collagen biosynthetic process |
| hematopoietic stem cell proliferation |
Sequence
MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 145 |
|
|||
| 219 |
|
|
||
| 230 |
|
|||
| 238 |
|
|||
| 285 |
|
|||
| 295 |
|
|||
| 296 |
|
|||
| 301 |
|
|||
| 361 |
|
|||
| 362 |
|
G49108TO
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Estrogen-dependent gene expression | Homo sapiens |
| Organic cation transport | Homo sapiens |
| Pre-NOTCH Transcription and Translation | Homo sapiens |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | Homo sapiens |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | Homo sapiens |
| RUNX1 regulates estrogen receptor mediated transcription | Homo sapiens |
| RUNX1 regulates expression of components of tight junctions | Homo sapiens |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | Homo sapiens |
| RUNX1 regulates transcription of genes involved in BCR signaling | Homo sapiens |
| RUNX1 regulates transcription of genes involved in WNT signaling | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
