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MIRAGE
Centromere protein C

Summary
UniProt ID
Q03188
Gene Symbol
  • CENPC
  • CENPC1
  • ICEN7
Gene ID
1060
Organism
Homo sapiens (human)
GlyGen
Q03188
PubChem
Q03188
The O-GlcNAc Database
Q03188
O-GlcNAcAtlas
Q03188
Re-Glyco
Q03188
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Centromere
  • Chromosome
  • DNA-binding
  • Isopeptide bond
  • Kinetochore
  • Mitosis
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Ubl conjugation
Gene Ontology (GO)
Displaying all 9 entries
GO Term
nucleus
kinetochore
midbody
condensed chromosome, centromeric region
nucleoplasm
cytosol
nuclear body
inner kinetochore
pericentric heterochromatin
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDLVRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
54
543
568
743
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 7 entries
Pathway Name Organism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Homo sapiens
Deposition of new CENPA-containing nucleosomes at the centromere Homo sapiens
EML4 and NUDC in mitotic spindle formation Homo sapiens
Mitotic Prometaphase Homo sapiens
RHO GTPases Activate Formins Homo sapiens
Resolution of Sister Chromatid Cohesion Homo sapiens
Separation of Sister Chromatids Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0060218 CREST syndrome
DOID:5082 liver cirrhosis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025