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Sodium channel subunit beta-1

Summary

UniProt ID

Q07699

Gene Symbol

SCN1B

Organism

Homo sapiens (human)

External Links

GlyGen: Q07699
PubChem: Q07699
The Human Metabolome Database: HMDBP09079

Annotation

Keyword

3D-structure
Alternative splicing
Atrial fibrillation
Brugada syndrome
Cell adhesion
Cell membrane
Cell projection
Disease variant
Disulfide bond
Epilepsy
Glycoprotein
Immunoglobulin domain
Reference proteome
Secreted
Signal
Sodium channel
Transmembrane helix
Voltage-gated channel

Gene Ontology (GO)

Displaying entries **11 - 19** of 19 in total

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1

2
GO Term
cardiac conduction
cardiac muscle cell action potential involved in contraction
membrane depolarization during cardiac muscle cell action potential
membrane depolarization during Purkinje myocyte cell action potential
regulation of sodium ion transmembrane transporter activity
regulation of ventricular cardiac muscle cell membrane repolarization
regulation of atrial cardiac muscle cell membrane depolarization
neuronal action potential propagation
corticospinal neuron axon guidance

Displaying **all 7** entries
GO Term
extracellular region
plasma membrane
T-tubule
perikaryon
voltage-gated sodium channel complex
intercalated disc
node of Ranvier

Displaying **all 6** entries
GO Term
sodium channel regulator activity
sodium channel inhibitor activity
transmembrane transporter binding
voltage-gated sodium channel activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
voltage-gated sodium channel activity involved in Purkinje myocyte action potential

Annotation information from UniProt.

Sequence

MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	Source
93	N-linked (GlcNAc...) asparagine	30765606 36696443	UniProt GlyGen
110	N-linked (GlcNAc...) asparagine	30190309 30765606 36696443	UniProt GlyGen
114	N-linked (GlcNAc...) asparagine	30190309 30765606 36696443	UniProt GlyGen
135	N-linked (GlcNAc...) asparagine	30765606 36696443 36823201	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Interaction between L1 and Ankyrins	Homo sapiens
Phase 0 - rapid depolarisation	Homo sapiens
Sensory perception of sweet, bitter, and umami (glutamate) taste	Homo sapiens