Sensory perception of sweet, bitter, and umami (glutamate) taste

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GRM1_HUMANGRM1(410-1194):L-GluL-GluGRM4_HUMANGRM4(309-912):L-GluL-Glu,L-AspL-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13GMP,IMPGTPL-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13GDPGNAT3:GTPTAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMPGNB1,3:GNG13TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13Sweet taste compoundsTAS1R2:TAS1R3:Sweet compound:GNAT3:GTP:GNB1,3:GNG13TAS1R2:TAS1R3:Sweet taste compoundsTAS2R:GNAT3:GDP:GNB1,3:GNG13TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13Ligand of TAS2R (non-orphan)TAS2R:ligand:GNAT3:GTP:GNB1,3:GNG13TAS2R (non-orphan):ligandGNB1,3:GNG13:PLCB2:Ca2+PLCB2:Ca2+PIP2DAGIP3H2OIP3-gated Ca-channel type 3 (open)IP3-gated Ca-channel type 3Ca2+Ca2+Na+Na+ATPATP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025