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Sodium channel subunit beta-2

Summary

UniProt ID

O60939

Gene Symbol

SCN2B

Organism

Homo sapiens (human)

External Links

GlyGen: O60939
PubChem: O60939
The Human Metabolome Database: HMDBP09081

Annotation

Keyword

3D-structure
Atrial fibrillation
Brugada syndrome
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Reference proteome
Signal
Sodium channel
Transmembrane helix
Voltage-gated channel

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

1

2

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GO Term
chemical synaptic transmission
nervous system development
gene expression
sodium ion transmembrane transport
cardiac muscle contraction
cardiac muscle cell action potential involved in contraction
membrane depolarization during cardiac muscle cell action potential
regulation of sodium ion transmembrane transporter activity
regulation of atrial cardiac muscle cell membrane depolarization
response to pyrethroid

Displaying **all 4** entries
GO Term
plasma membrane
synapse
T-tubule
voltage-gated sodium channel complex

Displaying **all 3** entries
GO Term
sodium channel regulator activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

Annotation information from UniProt.

Sequence

MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	Source
42	N-linked (GlcNAc...) asparagine		UniProt GlyGen
66	N-linked (GlcNAc...) asparagine	30765606	UniProt GlyGen
74	N-linked (GlcNAc...) asparagine		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Interaction between L1 and Ankyrins	Homo sapiens
Phase 0 - rapid depolarisation	Homo sapiens
Sensory perception of sweet, bitter, and umami (glutamate) taste	Homo sapiens