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Serine/threonine-protein kinase PAK 2
Summary
- UniProt ID
- Q13177
- Gene Symbol
-
- PAK2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Allosteric enzyme
- Apoptosis
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Growth regulation
- Host-virus interaction
- Membrane
- Myristate
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| postsynaptic density |
| perinuclear region of cytoplasm |
| nucleus |
| cytoplasm |
| plasma membrane |
| cell-cell junction |
| secretory granule |
| glutamatergic synapse |
| cytosol |
Sequence
MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSGTEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKGTEAPAVVTEEEDDDEETAPPVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 110 |
|
|||
| 169 |
|
|||
| 178 |
|
G80920RR
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of RAC1 | Homo sapiens |
| CD209 (DC-SIGN) signaling | Homo sapiens |
| CD28 dependent Vav1 pathway | Homo sapiens |
| CDC42 GTPase cycle | Homo sapiens |
| Ephrin signaling | Homo sapiens |
| FCERI mediated MAPK activation | Homo sapiens |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | Homo sapiens |
| Generation of second messenger molecules | Homo sapiens |
| MAPK6/MAPK4 signaling | Homo sapiens |
| Nef and signal transduction | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
