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Core-binding factor subunit beta

Summary

UniProt ID

Q13951

Gene Symbol

CBFB

Gene ID

865

Organism

Homo sapiens (human)

External Links

GlyGen: Q13951
PubChem: Q13951
The O-GlcNAc Database: Q13951
O-GlcNAcAtlas: Q13951
Re-Glyco: Q13951

Annotation

Keyword

3D-structure
Alternative splicing
Chromosomal rearrangement
Disease variant
Dwarfism
Nucleus
Phosphoprotein
Proto-oncogene
Reference proteome

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
core-binding factor complex
membrane
nucleoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
negative regulation of CD4-positive, alpha-beta T cell differentiation
negative regulation of transcription by RNA polymerase II
protein polyubiquitination
osteoblast differentiation
regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
definitive hemopoiesis
positive regulation of CD8-positive, alpha-beta T cell differentiation
lymphocyte differentiation
myeloid cell differentiation

Displaying **all 2** entries
GO Term
transcription coactivator activity
sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVATGTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLDGMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTTRP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
169			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 20** of 25 in total

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Pathway Name	Organism
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	Homo sapiens
RUNX1 regulates transcription of genes involved in interleukin signaling	Homo sapiens
RUNX2 regulates bone development	Homo sapiens
RUNX2 regulates chondrocyte maturation	Homo sapiens
RUNX2 regulates genes involved in cell migration	Homo sapiens
RUNX2 regulates genes involved in differentiation of myeloid cells	Homo sapiens
RUNX2 regulates osteoblast differentiation	Homo sapiens
RUNX3 Regulates Immune Response and Cell Migration	Homo sapiens
RUNX3 regulates RUNX1-mediated transcription	Homo sapiens
RUNX3 regulates p14-ARF	Homo sapiens