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Core-binding factor subunit beta

Summary

UniProt ID

Q13951

Gene Symbol

CBFB

Gene ID

865

Organism

Homo sapiens (human)

External Links

GlyGen: Q13951
PubChem: Q13951
The O-GlcNAc Database: Q13951
O-GlcNAcAtlas: Q13951
Re-Glyco: Q13951

Annotation

Keyword

3D-structure
Alternative splicing
Chromosomal rearrangement
Disease variant
Dwarfism
Nucleus
Phosphoprotein
Proto-oncogene
Reference proteome

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
membrane
nucleoplasm
core-binding factor complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
negative regulation of CD4-positive, alpha-beta T cell differentiation
negative regulation of transcription by RNA polymerase II
protein polyubiquitination
osteoblast differentiation
regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
definitive hemopoiesis
lymphocyte differentiation
myeloid cell differentiation
cell maturation

Displaying **all 2** entries
GO Term
transcription coactivator activity
sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVATGTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLDGMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTTRP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
169			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 25 in total

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Pathway Name	Organism
Estrogen-dependent gene expression	Homo sapiens
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	Homo sapiens
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Homo sapiens
RUNX1 regulates estrogen receptor mediated transcription	Homo sapiens
RUNX1 regulates expression of components of tight junctions	Homo sapiens
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Homo sapiens
RUNX1 regulates transcription of genes involved in BCR signaling	Homo sapiens
RUNX1 regulates transcription of genes involved in WNT signaling	Homo sapiens
RUNX1 regulates transcription of genes involved in differentiation of HSCs	Homo sapiens
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Homo sapiens