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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Rho guanine nucleotide exchange factor 6
Summary
- UniProt ID
- Q15052
- Gene Symbol
-
- ARHGEF6
- COOL2
- KIAA0006
- PIXA
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q15052
- PubChem
- Q15052
- The Human Metabolome Database
- HMDBP11457
- The O-GlcNAc Database
- Q15052
- O-GlcNAcAtlas
- Q15052
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell projection
- Guanine-nucleotide releasing factor
- Phosphoprotein
- Reference proteome
- SH3 domain
- Gene Ontology (GO)
| GO Term |
|---|
| JNK cascade |
| lamellipodium assembly |
| apoptotic process |
| GO Term |
|---|
| cytosol |
| cytoplasm |
| cell-cell junction |
| lamellipodium |
| GO Term |
|---|
| guanyl-nucleotide exchange factor activity |
| GTPase activator activity |
Sequence
MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDPQTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCGRSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 201 |
|
|||
| 243 |
|
G49108TO
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Homo sapiens |
| G alpha (12/13) signalling events | Homo sapiens |
| G beta:gamma signalling through CDC42 | Homo sapiens |
| NRAGE signals death through JNK | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RHOU GTPase cycle | Homo sapiens |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | Homo sapiens |
