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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Toll-like receptor 1
Summary
- UniProt ID
- Q15399
- Gene Symbol
-
- TLR1
- KIAA0012
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q15399
- PubChem
- Q15399
- The Human Metabolome Database
- HMDBP12415
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| detection of triacyl bacterial lipopeptide |
| cellular response to triacyl bacterial lipopeptide |
| GO Term |
|---|
| phagocytic vesicle membrane |
| Toll-like receptor 1-Toll-like receptor 2 protein complex |
| Golgi apparatus |
| plasma membrane |
| membrane |
| receptor complex |
| membrane raft |
Sequence
MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISELWTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLDLSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKEDPEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKLQTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLKALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNIDQVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSLCSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLEKEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKLTEQAKK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 51 | N-linked (GlcNAc...) asparagine |
|
||
| 137 | N-linked (GlcNAc...) asparagine |
|
||
| 163 | N-linked (GlcNAc...) asparagine | |||
| 248 |
|
|||
| 330 | N-linked (GlcNAc...) asparagine | |||
| 429 | N-linked (GlcNAc...) asparagine |
|
||
| 578 | N-linked (GlcNAc...) asparagine |
|
G80920RR
G99833VB
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Beta defensins | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| IRAK4 deficiency (TLR2/4) | Homo sapiens |
| MyD88 deficiency (TLR2/4) | Homo sapiens |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | Homo sapiens |
| Regulation of TLR by endogenous ligand | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| Toll Like Receptor TLR1:TLR2 Cascade | Homo sapiens |
