Proprotein convertase subtilisin/kexin type 7

Summary
UniProt ID
Q16549
Gene Symbol
  • PCSK7
  • LPC
  • PC7
  • PC8
  • SPC7
Organism
Homo sapiens (human)
External Links
GlyGen
Q16549
PubChem
Q16549
The Human Metabolome Database
HMDBP07934
Annotation
Keyword
  • Cleavage on pair of basic residues
  • Glycoprotein
  • Golgi apparatus
  • Palmitate
  • Reference proteome
  • Serine protease
  • Signal
  • Transmembrane helix
  • Zymogen
Gene Ontology (GO)
Displaying all 2 entries
GO Term
protein processing
peptide hormone processing
Displaying all 3 entries
GO Term
Golgi membrane
membrane
trans-Golgi network
Displaying all 2 entries
GO Term
peptidase activity
serine-type endopeptidase activity
Sequence
MPKGRQKVPHLDAPLGLPTCLWLELAGLFLLVPWVMGLAGTGGPDGQGTGGPSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQVEAVLAGHEAVRWHSEQRLLRRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGSVWSAVDIRDRQRLLESAMSGKYLHDDFALPCPPGLKIPEEDGYTITPNTLKTLVLVGCFTVFWTVYYMLEVYLSQRNVASNQVCRSGPCHWPHRSRKAKEEGTELESVPLCSSKDPDEVETESRGPPTTSDLLAPDLLEQGDWSLSQNKSALDCPHQHLDVPHGKEEQIC
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
167 N-linked (GlcNAc...) asparagine
175 N-linked (GlcNAc...) asparagine
241 N-linked (GlcNAc...) asparagine
511 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024