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MIRAGE
proprotein convertase subtilisin/kexin type 7

Summary
Gene Symbol
  • PCSK7
Organism
Homo sapiens (human)
NCBI Gene
9159
PubChem
9159
Alliance of Genome Resources
Annotation
Keyword
  • Cleavage on pair of basic residues
  • Glycoprotein
  • Golgi apparatus
  • Palmitate
  • Reference proteome
  • Serine protease
  • Signal
  • Transmembrane helix
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
Q16549
  • Lymphoma proprotein convertase
  • Prohormone convertase 7
  • Proprotein convertase 7
  • Proprotein convertase 8
  • Subtilisin/kexin-like protease PC7
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 3 entries
GO Term Evidence Code PMID
protein processing
protein processing
peptide hormone processing
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
proprotein convertase subtilisin/kexin type 7
Functional Category
  • L: Replication, recombination and repair
  • M: Cell wall/membrane/envelope biogenesis
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Displaying all 4 entries
Gene Ontology
hydrolase activity
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity
Displaying all 10 entries
InterPro
Galactose-binding-like domain superfamily
Kexin/furin catalytic domain
P domain
Peptidase S8, pro-domain superfamily
Peptidase S8, pro-domain
Peptidase S8, subtilisin, His-active site
Peptidase S8, subtilisin, Ser-active site
Peptidase S8, subtilisin-related
Peptidase S8/S53 domain superfamily
Peptidase S8/S53 domain
Ortholog
Displaying entries 1 - 10 of 101 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
5045 SGD:S000005182
5046 SGD:S000005182
5122 SGD:S000005182
5125 SGD:S000005182
9159 Xenbase:XB-GENE-950061
18548 SGD:S000005182
18550 SGD:S000005182
18551 SGD:S000005182
18552 SGD:S000005182
18553 SGD:S000005182
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025