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Rho guanine nucleotide exchange factor 2

Summary

UniProt ID

Q60875

Gene Symbol

Arhgef2
Kiaa0651
Lbcl1
Lfc

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60875
The O-GlcNAc Database: Q60875
RaftProt: Q60875

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Coiled coil
Cytoplasmic vesicle
Cytoskeleton
Developmental protein
Differentiation
Golgi apparatus
Guanine-nucleotide releasing factor
Innate immunity
Microtubule
Mitosis
Neurogenesis
Phosphoprotein
Proto-oncogene
Reference proteome
Tight junction
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

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GO Term
positive regulation of transcription by RNA polymerase II
cell morphogenesis
actin filament organization
negative regulation of microtubule depolymerization
innate immune response
negative regulation of neurogenesis
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of neuron differentiation
positive regulation of peptidyl-tyrosine phosphorylation

Displaying entries **1 - 10** of 16 in total

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2

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GO Term
podosome
spindle
postsynaptic density
ruffle membrane
postsynaptic density, intracellular component
cytoplasm
Golgi apparatus
cytoskeleton
microtubule
bicellular tight junction

Displaying **all 4** entries
GO Term
guanyl-nucleotide exchange factor activity
small GTPase binding
microtubule binding
metal ion binding

Annotation information from UniProt.

Sequence

MSRIESLTRARIDRSKEQATKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLRNNTALQSVSLRSKTTTRERPTSAIYPSDSFRQSLLGSRRGLSSLSLAKSVSTTNIAGHFNDESPLGLRQILSQSTDSLNMRNRTLSVESLIDEGVEVFYNELMSDFEMDEKDFEADSWSLAVDSSFLQQHKKEVMKKQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELQMEPEVVQGLFPCVDELSDIHTRFLNQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGSNAEQMRKTYSEFCSRHTKALKLYKELYARDKRFQQFIRKMTRSAVLKRHGVQECILLVTQRITKYPVLINRILQNSHGVEEEYQDLASALGLVKELLSNVDQDVHELEKEARLQEIYNRMDPRAQTPVPGKGPFGRDELLRRKLIHEGCLLWKTATGRFKDVLLLLMTDVLVFLQEKDQKYIFTSLDKPSVVSLQNLIVRDIANQAKGMFLISSGPPEMYEVHAASRDDRTTWIRVIQQSVRLCPSREDFPLIETEDKAYLRRIKTKLQQKNQALVELLQKNVELFAEMVHFQALKAGFVGMPPPALPRGLFRLESFESLRGERLLKDALREVEGLKDLLLGPCVDLPMTSREPALPLDSDSGSCPGVTANGEARTFNGSIELCRADSDSSQKDRNGNQLRSPQEEVLQPLINLYGLLHGLQAVVVQQERLMEALFPEGPERWEKLSRANSRDGEAGRAAVASVTPEKQATELALLQRQHTLLQEELRRCQRLGEERATEAGSLEARLRESEQARALLEREAEEIRRQLAALGQNEPLPAEAPWARRPLDPRRRSLPAGDALYLSFNPPQPSRGHDRLDLPVTVRSLHRPFDDREAQELGSPEDRLQDSSDPDTGSEEEVSSRLSPPHSPRDFTRMQDIPEETESRDGEPTASES

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites