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Rho guanine nucleotide exchange factor 2

Summary

UniProt ID

Q60875

Gene Symbol

Arhgef2
Kiaa0651
Lbcl1
Lfc

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q60875
The O-GlcNAc Database: Q60875
RaftProt: Q60875

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Coiled coil
Cytoplasmic vesicle
Cytoskeleton
Developmental protein
Differentiation
Golgi apparatus
Guanine-nucleotide releasing factor
Innate immunity
Microtubule
Mitosis
Neurogenesis
Phosphoprotein
Proto-oncogene
Reference proteome
Tight junction
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

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GO Term
positive regulation of transcription by RNA polymerase II
positive regulation of NF-kappaB transcription factor activity
establishment of mitotic spindle orientation
regulation of Rho protein signal transduction
cellular response to muramyl dipeptide
negative regulation of podosome assembly
cell morphogenesis
actin filament organization
negative regulation of microtubule depolymerization
innate immune response

Displaying entries **11 - 16** of 16 in total

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1

2
GO Term
cytoplasmic vesicle
protein-containing complex
vesicle
neuronal cell body
glutamatergic synapse
dendritic shaft

Displaying **all 4** entries
GO Term
microtubule binding
metal ion binding
guanyl-nucleotide exchange factor activity
small GTPase binding

Annotation information from UniProt.

Sequence

MSRIESLTRARIDRSKEQATKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLRNNTALQSVSLRSKTTTRERPTSAIYPSDSFRQSLLGSRRGLSSLSLAKSVSTTNIAGHFNDESPLGLRQILSQSTDSLNMRNRTLSVESLIDEGVEVFYNELMSDFEMDEKDFEADSWSLAVDSSFLQQHKKEVMKKQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELQMEPEVVQGLFPCVDELSDIHTRFLNQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGSNAEQMRKTYSEFCSRHTKALKLYKELYARDKRFQQFIRKMTRSAVLKRHGVQECILLVTQRITKYPVLINRILQNSHGVEEEYQDLASALGLVKELLSNVDQDVHELEKEARLQEIYNRMDPRAQTPVPGKGPFGRDELLRRKLIHEGCLLWKTATGRFKDVLLLLMTDVLVFLQEKDQKYIFTSLDKPSVVSLQNLIVRDIANQAKGMFLISSGPPEMYEVHAASRDDRTTWIRVIQQSVRLCPSREDFPLIETEDKAYLRRIKTKLQQKNQALVELLQKNVELFAEMVHFQALKAGFVGMPPPALPRGLFRLESFESLRGERLLKDALREVEGLKDLLLGPCVDLPMTSREPALPLDSDSGSCPGVTANGEARTFNGSIELCRADSDSSQKDRNGNQLRSPQEEVLQPLINLYGLLHGLQAVVVQQERLMEALFPEGPERWEKLSRANSRDGEAGRAAVASVTPEKQATELALLQRQHTLLQEELRRCQRLGEERATEAGSLEARLRESEQARALLEREAEEIRRQLAALGQNEPLPAEAPWARRPLDPRRRSLPAGDALYLSFNPPQPSRGHDRLDLPVTVRSLHRPFDDREAQELGSPEDRLQDSSDPDTGSEEEVSSRLSPPHSPRDFTRMQDIPEETESRDGEPTASES

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites