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Transferrin receptor protein 1

Summary

UniProt ID

Q62351

Gene Symbol

Tfrc
Trfr

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0005594

GlyConnect

2776

GlyGen

Q62351

PubChem

Q62351

The O-GlcNAc Database

Q62351

RaftProt

Q62351

Annotation

Keyword

Cell membrane
Direct protein sequencing
Disulfide bond
Endocytosis
Glycoprotein
Palmitate
Phosphoprotein
Receptor
Reference proteome
Signal-anchor
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 26 in total

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GO Term
iron ion transport
intracellular iron ion homeostasis
osteoclast differentiation
positive regulation of isotype switching
positive regulation of B cell proliferation
positive regulation of protein-containing complex assembly
intracellular signal transduction
positive regulation of T cell proliferation
negative regulation of apoptotic process
positive regulation of bone resorption

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GO Term
extracellular space
plasma membrane
membrane
cytoplasmic vesicle
melanosome
extracellular exosome
recycling endosome membrane
HFE-transferrin receptor complex
basolateral plasma membrane
endosome

Displaying **all 8** entries
GO Term
iron ion transmembrane transporter activity
protein-containing complex binding
protein kinase binding
protein-folding chaperone binding
Hsp70 protein binding
protein homodimerization activity
double-stranded RNA binding
transferrin receptor activity

Annotation information from UniProt.

Sequence

MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAADEEENADNNMKASVRKPKRFNGRLCFAAIALVIFFLIGFMSGYLGYCKRVEQKEECVKLAETEETDKSETMETEDVPTSSRLYWADLKTLLSEKLNSIEFADTIKQLSQNTYTPREAGSQKDESLAYYIENQFHEFKFSKVWRDEHYVKIQVKSSIGQNMVTIVQSNGNLDPVESPEGYVAFSKPTEVSGKLVHANFGTKKDFEELSYSVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKNKFPVVEADLALFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEKLFGKMEGSCPARWNIDSSCKLELSQNQNVKLIVKNVLKERRILNIFGVIKGYEEPDRYVVVGAQRDALGAGVAAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDFGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPVDGKSLYRDSNWISKVEKLSFDNAAYPFLAYSGIPAVSFCFCEDADYPYLGTRLDTYEALTQKVPQLNQMVRTAAEVAGQLIIKLTHDVELNLDYEMYNSKLLSFMKDLNQFKTDIRDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLKLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
104	O-linked (GalNAc...) threonine			UniProt GlyGen
253	N-linked (GlcNAc...) asparagine		G77547TA	UniProt GlyGen
319	N-linked (GlcNAc...) asparagine			UniProt GlyGen
725	N-linked (GlcNAc...) asparagine	19349973	G72747WU G05724UK G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
730	N-linked (GlcNAc...) asparagine	19349973	G47246VB G05724UK	GlycoProtDB UniProt GlyGen GlyConnect
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
Golgi Associated Vesicle Biogenesis	Mus musculus
RAC1 GTPase cycle	Mus musculus
RAC2 GTPase cycle	Mus musculus
RAC3 GTPase cycle	Mus musculus
RHOA GTPase cycle	Mus musculus
RHOB GTPase cycle	Mus musculus
RHOC GTPase cycle	Mus musculus
RHOG GTPase cycle	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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External Links

Annotation

International Collaboration

Acknowledgements