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Transferrin receptor protein 1

Summary

UniProt ID

Q62351

Gene Symbol

Tfrc
Trfr

Gene ID

22042

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0005594

GlyConnect

Transferrin receptor protein 1

GlyGen

Q62351

PubChem

Q62351

RaftProt

Q62351

Re-Glyco

Q62351

Annotation

Keyword

Cell membrane
Direct protein sequencing
Disulfide bond
Endocytosis
Glycoprotein
Palmitate
Phosphoprotein
Receptor
Reference proteome
Signal-anchor
Transmembrane helix

Gene Ontology (GO)

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GO Term
membrane
cytoplasmic vesicle
melanosome
postsynapse
endosome
early endosome
external side of plasma membrane
cell surface
basolateral plasma membrane
perinuclear region of cytoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
response to hypoxia
transferrin transport
multicellular organismal-level iron ion homeostasis
cellular response to xenobiotic stimulus
positive regulation of protein localization to nucleus
cellular response to leukemia inhibitory factor
positive regulation of canonical NF-kappaB signal transduction
negative regulation of mitochondrial fusion
positive regulation of protein-containing complex assembly
response to copper ion

Displaying **all 7** entries
GO Term
protein homodimerization activity
protein-containing complex binding
iron ion transmembrane transporter activity
double-stranded RNA binding
transferrin receptor activity
protein kinase binding
Hsp70 protein binding

Annotation information from UniProt.

Sequence

MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAADEEENADNNMKASVRKPKRFNGRLCFAAIALVIFFLIGFMSGYLGYCKRVEQKEECVKLAETEETDKSETMETEDVPTSSRLYWADLKTLLSEKLNSIEFADTIKQLSQNTYTPREAGSQKDESLAYYIENQFHEFKFSKVWRDEHYVKIQVKSSIGQNMVTIVQSNGNLDPVESPEGYVAFSKPTEVSGKLVHANFGTKKDFEELSYSVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKNKFPVVEADLALFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEKLFGKMEGSCPARWNIDSSCKLELSQNQNVKLIVKNVLKERRILNIFGVIKGYEEPDRYVVVGAQRDALGAGVAAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDFGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPVDGKSLYRDSNWISKVEKLSFDNAAYPFLAYSGIPAVSFCFCEDADYPYLGTRLDTYEALTQKVPQLNQMVRTAAEVAGQLIIKLTHDVELNLDYEMYNSKLLSFMKDLNQFKTDIRDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLKLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
104	O-linked (GalNAc...) threonine			UniProt GlyGen
253	N-linked (GlcNAc...) asparagine		G77547TA	UniProt GlyGen
319	N-linked (GlcNAc...) asparagine			UniProt GlyGen
725	N-linked (GlcNAc...) asparagine	19349973	G72747WU G05724UK G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
730	N-linked (GlcNAc...) asparagine	19349973	G47246VB G05724UK	GlycoProtDB UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
Golgi Associated Vesicle Biogenesis	Mus musculus
RAC1 GTPase cycle	Mus musculus
RAC2 GTPase cycle	Mus musculus
RAC3 GTPase cycle	Mus musculus
RHOA GTPase cycle	Mus musculus
RHOB GTPase cycle	Mus musculus
RHOC GTPase cycle	Mus musculus
RHOG GTPase cycle	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:4258	Weissenbacher-Zweymuller syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements