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NADPH oxidase 3

Summary

UniProt ID: Q672K1
Gene Symbol: Nox3
Gene ID: 292279
Organism: Rattus norvegicus (Norway rat)

External Links

PubChem: Q672K1
Re-Glyco: Q672K1

Annotation

Keyword: Cell membrane Glycoprotein Heme Oxidoreductase Reference proteome Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
temperature homeostasis	ISO	GO_REF
defense response	IBA	GO_REF
detection of gravity	ISO	GO_REF
response to gravity	ISO	GO_REF
superoxide anion generation	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

superoxide anion generation

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis

developmental process [inference]

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

otolith development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis

response to stimulus [inference]

response to stress [inference]

defense response

response to external stimulus [inference]

detection of external stimulus [inference]

detection of gravity

response to abiotic stimulus [inference]

detection of abiotic stimulus [inference]

detection of gravity

response to gravity

detection of gravity

detection of stimulus [inference]

detection of external stimulus [inference]

detection of gravity

detection of abiotic stimulus [inference]

detection of gravity

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GO Term	Evidence Code	Reference
cytoplasm	ISO	GO_REF
cytoplasm	IEA	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

NADPH oxidase complex

catalytic complex [inference]

oxidoreductase complex [inference]

NADPH oxidase complex

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

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GO Term	Evidence Code	Reference
NAD(P)H oxidase H2O2-forming activity	IBA	GO_REF
superoxide-generating NAD(P)H oxidase activity	ISS	GO_REF
superoxide-generating NAD(P)H oxidase activity	ISO	GO_REF
superoxide-generating NAD(P)H oxidase activity	IBA	GO_REF
superoxide-generating NAD(P)H oxidase activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on NAD(P)H [inference]

oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [inference]

NAD(P)H oxidase H2O2-forming activity

superoxide-generating NAD(P)H oxidase activity

superoxide-generating NADPH oxidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPTCWILNESVSFVVALLWLAINIYLFIDTFCWYAEEESFFYTRVILGSALAWARASAVCLNFNCMLILLPVSRNFVSLVRGTSVCCRGPWRRQLDKNLKFHKLVAYGIAVNSVIHIVAHLFNLERYHLGQAKDAEGLLAALSKLGNAPNESYLNPVRTLYTGTTTQLLMTVSGITGLVISLALILIMTSSTEFIRQSSYELFWYTHHIFIFLFISLAIHGGGRIIRGQTPESLRLHNVTFCRDHFDEWQEAASCPVPQFSGKEPSAWKWTLGPVVLYACEIIIRFWRSHQEVVITKVVSHPSAVLELHMKKRDFKMAPGQYIFIQCPSISPLEWHPFTLTSAPQEDFFSVHIRASGDWTEALLKAFGAEGQAPSELCSMPRLAVDGPFGGSLADVFHYPVSVCIATGIGVTPFASLLKSVWYKCCESQSLPGLSKVYFYWICRDAAAFEWFADLLLSLETQMSEQGKAHLLSYHIYLTGWDEYQAIHIALHWDESLDVITGLKQKTFYGRPNWNEEFKQIAYNHPSSSIGVFFCGPKAMSKTLQKMCRLYSSSDPRGVHFYYNKENF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
238	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
RAC1 GTPase cycle	Rattus norvegicus
RAC3 GTPase cycle	Rattus norvegicus
RHO GTPases Activate NADPH Oxidases	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

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International Collaboration

Acknowledgements