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Grainyhead-like protein 2 homolog

Summary

UniProt ID

Q6ISB3

Gene Symbol

GRHL2
BOM
TFCP2L3

Organism

Homo sapiens (human)

External Links

GlyGen: Q6ISB3
The O-GlcNAc Database: Q6ISB3
O-GlcNAcAtlas: Q6ISB3

Annotation

Keyword

3D-structure
Activator
Alternative splicing
Corneal dystrophy
DNA-binding
Disease variant
Dwarfism
Ectodermal dysplasia
Membrane
Non-syndromic deafness
Nucleus
Reference proteome
Transcription regulation

Gene Ontology (GO)

Displaying entries **21 - 22** of 22 in total

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3
GO Term
positive regulation of transcription by RNA polymerase II
embryonic digit morphogenesis

Displaying **all 5** entries
GO Term
chromatin
nucleus
cell-cell junction
membrane
nucleoplasm

Displaying **all 10** entries
GO Term
DNA-binding transcription factor binding
chromatin DNA binding
identical protein binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
intronic transcription regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MSQESDNNKRLVALVPMPSDPPFNTRRAYTSEDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRDKRLLSVSKASDSQEDQEKRNCLGTSEAQSNLSGGENRVQVLKTVPVNLSLNQDHLENSKREQYSISFPESSAIIPVSGITVVKAEDFTPVFMAPPVHYPRGDGEEQRVVIFEQTQYDVPSLATHSAYLKDDQRSTPDSTYSESFKDAATEKFRSASVGAEEYMYDQTSSGTFQYTLEATKSLRQKQGEGPMTYLNKGQFYAITLSETGDNKCFRHPISKVRSVVMVVFSEDKNRDEQLKYWKYWHSRQHTAKQRVLDIADYKESFNTIGNIEEIAYNAVSFTWDVNEEAKIFITVNCLSTDFSSQKGVKGLPLMIQIDTYSYNNRSNKPIHRAYCQIKVFCDKGAERKIRDEERKQNRKKGKGQASQTQCNSSSDGKLAAIPLQKKSDITYFKTMPDLHSQPVLFIPDVHFANLQRTGQVYYNTDDEREGGSVLVKRMFRPMEEEFGPVPSKQMKEEGTKRVLLYVRKETDDVFDALMLKSPTVKGLMEAISEKYGLPVEKIAKLYKKSKKGILVNMDDNIIEHYSNEDTFILNMESMVEGFKVTLMEI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites