NAD(+) hydrolase SARM1
| GO Term |
|---|
| cytoplasm |
| mitochondrion |
| axon |
| dendrite |
| neuromuscular junction |
| protein-containing complex |
| synapse |
| cell surface |
| mitochondrial outer membrane |
| microtubule |
| GO Term |
|---|
| signaling adaptor activity |
| NAD+ nucleotidase, cyclic ADP-ribose generating |
| NAD+ nucleosidase activity |
| NAD(P)+ nucleosidase activity |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 240 |
|
|||
| 383 |
|
| Pathway Name | Organism |
|---|---|
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | Mus musculus |
| IKK complex recruitment mediated by RIP1 | Mus musculus |
| MyD88-independent TLR4 cascade | Mus musculus |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | Mus musculus |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025