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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NAD(+) hydrolase SARM1
Summary
- UniProt ID
- Q6PDS3
- Gene Symbol
-
- Sarm1
- Kiaa0524
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cell projection
- Cytoplasm
- Differentiation
- Hydrolase
- Innate immunity
- Mitochondrion
- NAD
- Neurogenesis
- Phosphoprotein
- Reference proteome
- Repeat
- Synapse
- Transit peptide
- Gene Ontology (GO)
| GO Term |
|---|
| NAD catabolic process |
| negative regulation of MyD88-independent toll-like receptor signaling pathway |
| GO Term |
|---|
| cytoplasm |
| microtubule |
| microtubule cytoskeleton |
| axon |
| protein-containing complex |
| synapse |
| dendrite |
| mitochondrion |
| mitochondrial outer membrane |
| cell surface |
| GO Term |
|---|
| NAD(P)+ nucleosidase activity |
| NAD+ nucleotidase, cyclic ADP-ribose generating |
| NAD+ nucleosidase activity |
| signaling adaptor activity |
Sequence
MVLTLLFSAYKLCRFFTMSGPRPGADRLTVPGPDRSGGASPWWAAGGRGSREVSPGVGTEVQGALERSLPELQQALSELKQASAARAVGAGLAEVFQLVEEAWLLPAVGREVAQGLCDAIRLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLAKEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALANCALHGGQTVQRCMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVEHSGTLALVEPLVASLDPGRFARCLVDASDTSQGRGPDDLQSLVLLLDSSRLEAQCIGAFYLCAEAAIKSLQGKTKVFSDIGAIQSLKRLVSYSTNGTTSALAKRALRLLGEEVPRRILPCVASWKEAEVQTWLQQIGFSQYCENFREQQVDGDLLLRLTDEELQTDLGMKSSITRKRFFRELTELKTFASYATCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIRLGVHRTRILSAAREMLHSPLPCTGGKLSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVIAARNFVLVLSAGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPIIDGFEWPEPQALPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQGRPSQDSSAGSDTSLEGATPMGLP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 240 |
|
|||
| 383 |
|
G49108TO
G14972EH
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | Mus musculus |
| IKK complex recruitment mediated by RIP1 | Mus musculus |
| MyD88-independent TLR4 cascade | Mus musculus |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | Mus musculus |
