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MIRAGE
Desmoglein-4

Summary
UniProt ID
Q6W3B0
Gene Symbol
  • Dsg4
Gene ID
291754
Organism
Rattus norvegicus (Norway rat)
Re-Glyco
Q6W3B0
Annotation
Keyword
  • Calcium
  • Cell adhesion
  • Cell junction
  • Cell membrane
  • Cleavage on pair of basic residues
  • Disease variant
  • Glycoprotein
  • Metal-binding
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 2 entries
GO Term
plasma membrane
desmosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
calcium ion binding
Annotation information from UniProt.
Sequence
MDWLLFRNICLLILFMVVLGVNSEFIVEVKELDIENGTTTWQTVRRQKREWIKFAAACREGEDNSKRNPIARIRSDCEVSQRITYRISGAGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIHCRALNSRGEDLERPLELRVKVMDVNDNPPVFTQNVYTANIEENSDANALVVKLSATDADEDNHLNSKIAYKIISQEPAGAPMFMVNRYTGEVRTMSNFLDREQHSMYNLLVRGSDRDGATDGLSSECDCRIKILDVNDNFPILEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYSILSGNDGNWFEIQTDPKTNEGILKLVKMLDYEQEPNIYLSIGVRNQAEFHHSVASQFQMHSTPVRIQVINVREGPTFRPSSMTFSLRGGMRGDSLMNYVLGTYTAIDMDTGSPATNVRYVIGHDAGSWLKVDSRTGEIQFSREFDTKSKYITDGMYAAEILAIDDGSGRTATGTICIEVPDANDYCPVIYAESRSVCTHASSVRIYVNDHSFGAPFTFCVVDESPDTADIWDIRSINGTSAILMTEQTLSPGPYQIPILVKDSHNRACELPQTVLLDACLCDDYHVCLHSSTTGIYTGDTIWVTDDMGTVTDDGLRQSNVGLGPAGIGMIILGLLLLFLSPLLLLMCCCKRRQPEGLGTRFAPVPEGGEGVMQPWRIEGAHPEDRDVSNICVPMTASNTQDRIDSSEIYTNTYAGGGTVEGGVSGVELNTGVGTAAGIAAGGATGTLRKRSSTIGTLREYQDTGMNMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGTGSPVGSIGCCSWIVDDLDESYMETLDPKFRTLAEICLDTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGMTLSEAEFQAEMAAASEPMIHGDIIVTETYTATDPCVQPTTIVFDSQLPPNVVVTETVMAPVYDVQGNICVPAEIANTHNVYYAERVVASPGVPDMGNGNIGDTCIGPVMSGGILVGPEIQVTQMMSPDIHISQTTRSTSPMTSQHRVTRYSNIHYSRQ
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
110 N-linked (GlcNAc...) asparagine
545 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Formation of the cornified envelope Rattus norvegicus
Keratinization Rattus norvegicus
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:4535 hypotrichosis
DOID:987 alopecia
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025