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Broad substrate specificity ATP-binding cassette transporter ABCG2
Summary
- UniProt ID
- Q80W57
- Gene Symbol
-
- Abcg2
- Bcrp1
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- Q80W57
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Disulfide bond
- Glycoprotein
- Lipid transport
- Mitochondrion
- Phosphoprotein
- Reference proteome
- Translocase
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| apical plasma membrane |
| brush border membrane |
| mitochondrial membrane |
| membrane raft |
| external side of apical plasma membrane |
Sequence
MSSSNDHVLVPMSQRNKNGLPGMSSRGARTLAEGDVLSFHHITYRVKVKSGFLVRKTAEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPRGLSGDVLINGAPQPANFKCSSGYVVQDDVVMGTLTVRENLQFSAALRLPKAMKTHEKNERINTIIKELGLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKALEYFASAGYHCEPYNNPADFFLDVINGDSSAVMLNRGEQDHEANKTEEPSKREKPIIENLAEFYINSTIYGETKAELDQLPVAQKKKGSSAFREPVYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGALYFGLKNDPTGMQNRAGVFFFLTTNQCFTSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKLVSDLLPMRFLPSVIYTCILYFMLGLKRTVEAFFIMMFTLIMVAYTASSMALAIAAGQSVVSVATLLMTISFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQHNEFLGQEFCPGLNVTMNSTCVNSYTICTGNDYLINQGIDLSPWGLWRNHVALACMIIIFLTIAYLKLLFLKKYS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| APAP ADME | Rattus norvegicus |
| Ciprofloxacin ADME | Rattus norvegicus |
| Heme biosynthesis | Rattus norvegicus |
| Heme degradation | Rattus norvegicus |
| Iron uptake and transport | Rattus norvegicus |
| Sphingolipid de novo biosynthesis | Rattus norvegicus |
