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MIRAGE
Peroxisome proliferator-activated receptor gamma coactivator 1-beta
Summary
- UniProt ID
- Q86YN6
- Gene Symbol
-
- PERC
- PGC1
- PGC1B
- PPARGC1
- PPARGC1B
- Gene ID
- 133522
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- Nucleus
- Phosphoprotein
- RNA-binding
- Reference proteome
- Repeat
- Transcription regulation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| mitochondrion |
| nucleoplasm |
| cytosol |
| mediator complex |
| GO Term |
|---|
| transcription coregulator activity |
| RNA binding |
| nuclear estrogen receptor binding |
| nuclear receptor coactivator activity |
| AF-2 domain binding |
Sequence
MAGNDCGALLDEELSSFFLNYLADTQGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEALLAELTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQAGLRSKSQRPCVKADSTQDKKAPMMQSQSRSCTELHKHLTSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALGRADPGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPEPLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQIPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLEDWPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCSRSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRGEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQLSYGGLRHFCWPRYTDYDSNSEEALPASGKSKYEAMDFDSLLKEAQQSLH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 197 |
|
|||
| 198 |
|
|||
| 830 |
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | Homo sapiens |
| PPARA activates gene expression | Homo sapiens |
| Regulation of RUNX2 expression and activity | Homo sapiens |
| Transcriptional activation of mitochondrial biogenesis | Homo sapiens |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9970 | obesity |
