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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

Summary

UniProt ID

Q8BTI9

Gene Symbol

Pik3cb

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8BTI9
PubChem: Q8BTI9
O-GlcNAcAtlas: Q8BTI9

Annotation

Keyword

3D-structure
ATP-binding
Autophagy
Cell adhesion
Cytoplasm
Endocytosis
Kinase
Lipid metabolism
Nucleus
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 10** of 27 in total

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GO Term
regulation of cell-matrix adhesion
response to ischemia
sphingosine-1-phosphate receptor signaling pathway
homophilic cell adhesion via plasma membrane adhesion molecules
phosphatidylinositol-mediated signaling
positive regulation of Rac protein signal transduction
negative regulation of MAPK cascade
negative regulation of vascular endothelial growth factor signaling pathway
negative regulation of sprouting angiogenesis
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

Displaying **all 10** entries
GO Term
cytosol
nucleoplasm
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA
nucleus
nucleolus
cytoplasm
plasma membrane
midbody
brush border membrane

Displaying **all 7** entries
GO Term
kinase activity
insulin receptor substrate binding
1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity
1-phosphatidylinositol-3-kinase activity
ATP binding
1-phosphatidylinositol-4-phosphate 3-kinase activity
protein serine kinase activity

Annotation information from UniProt.

Sequence

MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAENATALHITFPENKKQPCYYPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLSRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
715			G49108TO	GlyGen
718			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 22 in total

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Pathway Name	Organism
DAP12 signaling	Mus musculus
Downstream TCR signaling	Mus musculus
Downstream signal transduction	Mus musculus
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Mus musculus
GPVI-mediated activation cascade	Mus musculus
IRS-mediated signalling	Mus musculus
Interleukin receptor SHC signaling	Mus musculus
Interleukin-3, Interleukin-5 and GM-CSF signaling	Mus musculus
PI3K Cascade	Mus musculus
PI3K/AKT Signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements