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MIRAGE
Rho guanine nucleotide exchange factor 10

Summary
UniProt ID
Q8C033
Gene Symbol
  • Arhgef10
  • Kiaa0294
Gene ID
234094
Organism
Mus musculus (house mouse)
GlyGen
Q8C033
PubChem
Q8C033
Re-Glyco
Q8C033
Annotation
Keyword
  • Alternative splicing
  • Coiled coil
  • Guanine-nucleotide releasing factor
  • Methylation
  • Phosphoprotein
  • Reference proteome
Gene Ontology (GO)
Displaying 1 entry
GO Term
centrosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MEQGEASPPVPAEHEAKCDTSNNEEEGELFDFDSGDEVPEADRQVPSADDRTRGAEAGGADENTCPAGNGTGAEPAPEAEPAKLVVPTKVNPYSVIDITPLQEDQPSSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAETVGDGQCNSLSSEDLPHSSEQGSQEGSALARWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGEEGGNSSPEYGWSSSEFESYEEPSDSEGKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEIQQAKQRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGGSFIRTRSLVSQDHRCYFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLRMVFYRVKEILQCHSMFQIALASRVSEWDVVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSGNRYLVRSDDVIETVYNDRGEIVKTKQRRIFMLNDVLMCATASSRNSHESHAVMSQRYLLKWSVPLGHVDVIQYNGGSGAGEHCRHHAAHSPESLAVVANAKPHKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLNQSVAHDWTSGLQRLILRKEDAIRAADRCRIQLQLPGKQDKSGRPTFFTAVFNTLTPAIKESWVSSLQMAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVAKQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQGSNPKVIECFNVESRILCMVYIPAEESKPQETTETKDPEATASRAPHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYAPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASVETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVSATAFQNKDRARDSPRSGSELQDEDPKDLLCSEEGPSCPGQPDTYTSVWLGDSLGLPTQKNDLSSSSGSLNLSHGSSSLEHRSVDSSLCDLLRDPSASPRSRPQGSRRARASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLGM
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
757
885
1264
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 7 entries
Pathway Name Organism
CDC42 GTPase cycle Mus musculus
G alpha (12/13) signalling events Mus musculus
NRAGE signals death through JNK Mus musculus
RAC1 GTPase cycle Mus musculus
RHOA GTPase cycle Mus musculus
RHOB GTPase cycle Mus musculus
RHOC GTPase cycle Mus musculus
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0060041 autism spectrum disorder
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025