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Nicastrin
Summary
- UniProt ID
- Q8CGU6
- Gene Symbol
-
- Ncstn
- Gene ID
- 289231
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative splicing
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Notch signaling pathway
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| lysosome |
| plasma membrane |
| membrane |
| cytoplasmic vesicle membrane |
| protein-containing complex |
| melanosome |
| synaptic membrane |
| early endosome |
| endoplasmic reticulum |
| Golgi apparatus |
Sequence
MATARGGSGPDPGSRGLLLLSFSVVLAGLCGGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEDDLKWVLTDGPNPPYMVLLEGKLFTRDIMEKLKGETSRIAGLAVTLAKPNSTSSFSPSVQCPNDGFGIYSNSYGPEFAHCKKTLWNELGNGLAYDDFSFPIFLLEDENETKVIKQCYQDHNLGQNGSAPSFPLCAMQLFSHMHAVISTATCMRRSFIQSTFSINPEIVCDPLSDYNVWSMLKPINTSGGLEPDVRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALHKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMENGKFPVRLENIDSFVELGQVALRTSLELWMHTDPMSQKNESVKNQVEDLLVTLEQSGADTPQVVLSRLVQSQALPPSSLQRFLRARNISGVVLADHSGSFHNRYYQSIYDTAENINVTYPESQSPEEDLNFVTDTAKALADVATVLARALYKLAGGTNFNNSIQADPQTVTRLLYGFLVRANNSWFQSILRHDLRSYLDDGPLQHYIAVSSPTNTTYVVQYALANLTGKVTNLTQEQCQDPSKVPNESKDLYEYSWVQGPWNSNKTERLPRCVRSTVRLARALSPAFELSQWSSTEYSTWAESRWKDIQARIFLIASKELEFITLIVGFSILVFSLIVTYCINAKADVLFVAPREPGAVSY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 44 | N-linked (GlcNAc...) asparagine |
|
||
| 54 | N-linked (GlcNAc...) asparagine |
|
||
| 128 | N-linked (GlcNAc...) asparagine |
|
||
| 186 | N-linked (GlcNAc...) asparagine |
|
||
| 203 | N-linked (GlcNAc...) asparagine |
|
||
| 263 | N-linked (GlcNAc...) asparagine |
|
||
| 386 | N-linked (GlcNAc...) asparagine |
|
||
| 434 | N-linked (GlcNAc...) asparagine | |||
| 463 | N-linked (GlcNAc...) asparagine |
|
||
| 507 | N-linked (GlcNAc...) asparagine |
|
G60230HH
G80920RR
G14548ZL
G62765YT
G09775CH
G31852PQ
G37135JQ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| EPH-ephrin mediated repulsion of cells | Rattus norvegicus |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | Rattus norvegicus |
| NRIF signals cell death from the nucleus | Rattus norvegicus |
| Neutrophil degranulation | Rattus norvegicus |
| Noncanonical activation of NOTCH3 | Rattus norvegicus |
| Nuclear signaling by ERBB4 | Rattus norvegicus |
| Regulated proteolysis of p75NTR | Rattus norvegicus |
| TGFBR3 PTM regulation | Rattus norvegicus |
