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Fermitin family homolog 2

Summary

UniProt ID

Q8CIB5

Gene Symbol

Fermt2
Plekhc1

Gene ID

218952

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8CIB5
PubChem: Q8CIB5
RaftProt: Q8CIB5
Re-Glyco: Q8CIB5

Annotation

Keyword

3D-structure
Cell adhesion
Cell junction
Cell membrane
Cell projection
Cell shape
Cytoskeleton
Lipid-binding
Nucleus
Phosphoprotein
Reference proteome
Wnt signaling pathway

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

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GO Term
I band
lamellipodium membrane
nucleoplasm
cytosol
adherens junction
cell surface
nucleus
cytoplasm
cell cortex
stress fiber

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 27 in total

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GO Term
positive regulation of myosin light chain kinase activity
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
regulation of cell shape
positive regulation of epithelial to mesenchymal transition
integrin activation
substrate adhesion-dependent cell spreading
negative regulation of fat cell differentiation
positive regulation of stress fiber assembly

Displaying **all 5** entries
GO Term
protein kinase binding
type I transforming growth factor beta receptor binding
SMAD binding
actin filament binding
phosphatidylinositol-3,4,5-trisphosphate binding

Annotation information from UniProt.

Sequence

MALDGIRMPDGCYADGTWELSVHVTDLNRDVTLRVTGEVHIGGVMLKLVEKLDVKKDWSDHALWWEKKRTWLLKTHWTLDKCGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLKKPRDPTKKKKKKLDDQSEDEALELEGPLIMPGSGSIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPVTSPEILAKMFKPQALLDKAKTNQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWALLLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKQYWCTFKDTSISCYKSREESSGTPAHQLNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIPDQITTDVNPECLVSPRYLKKYKSKQITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKREELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites