Voltage-dependent calcium channel subunit alpha-2/delta-3

Summary
UniProt ID
Q8IZS8
Gene Symbol
  • CACNA2D3
Organism
Homo sapiens (human)
External Links
PubChem
Q8IZS8
The Human Metabolome Database
HMDBP07486
Annotation
Keyword
  • Alternative splicing
  • Calcium channel
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Phosphoprotein
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Voltage-gated channel
Gene Ontology (GO)
Displaying 1 entry
GO Term
voltage-gated calcium channel complex
Sequence
MAGPGSPRRASRGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGPVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGAHGLLDPYNAFLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQKLKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCESVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSLQAQTVLLLLPLLLMLFSR
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
166 N-linked (GlcNAc...) asparagine
309 N-linked (GlcNAc...) asparagine
553 N-linked (GlcNAc...) asparagine
632 N-linked (GlcNAc...) asparagine
793 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Presynaptic depolarization and calcium channel opening Homo sapiens
Disease
Displaying entries 21 - 28 of 28 in total
DO ID Disease Name Source
DOID:4015 sarcomatoid carcinoma
DOID:4766 embryoma
DOID:5076 mixed glioma
DOID:5419 schizophrenia
DOID:5517 stomach carcinoma
DOID:9119 acute myeloid leukemia
DOID:9261 nasopharynx carcinoma
DOID:9460 uterine corpus cancer

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024