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RAS guanyl-releasing protein 4

Summary

UniProt ID

Q8TDF6

Gene Symbol

RASGRP4

Organism

Homo sapiens (human)

External Links

GlyGen: Q8TDF6
PubChem: Q8TDF6
The Human Metabolome Database: HMDBP08437
The O-GlcNAc Database: Q8TDF6

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cell membrane
Cytoplasm
Differentiation
Guanine-nucleotide releasing factor
Lipid-binding
Reference proteome
Zinc-finger

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
Ras protein signal transduction
positive regulation of Ras protein signal transduction
activation of phospholipase C activity
transmembrane receptor protein tyrosine kinase signaling pathway
regulation of G protein-coupled receptor signaling pathway
cell population proliferation
myeloid cell differentiation
response to extracellular stimulus

Displaying **all 4** entries
GO Term
plasma membrane
membrane
cytosol
nucleoplasm

Displaying **all 4** entries
GO Term
guanyl-nucleotide exchange factor activity
calcium ion binding
diacylglycerol binding
GTP-dependent protein binding

Annotation information from UniProt.

Sequence

MNRKDSKRKSHQECTGKIGGRGRPRQVRRHKTCPSPREISKVMASMNLGLLSEGGCSEDELLEKCIQSFDSAGSLCHEDHMLNMVLAMHSWVLPSADLAARLLTSYQKATGDTQELRRLQICHLVRYWLMRHPEVMHQDPQLEEVIGRFWATVAREGNSAQRRLGDSSDLLSPGGPGPPLPMSSPGLGKKRKVSLLFDHLETGELAQHLTYLEFRSFQAITPQDLRSYVLQGSVRGCPALEGSVGLSNSVSRWVQVMVLSRPGPLQRAQVLDKFIHVAQRLHQLQNFNTLMAVTGGLCHSAISRLKDSHAHLSPDSTKALLELTELLASHNNYARYRRTWAGCAGFRLPVLGVHLKDLVSLHEAQPDRLPDGRLHLPKLNNLYLRLQELVALQGQHPPCSANEDLLHLLTLSLDLFYTEDEIYELSYAREPRCPKSLPPSPFNAPLVVEWAPGVTPKPDRVTLGRHVEQLVESVFKNYDPEGRGTISQEDFERLSGNFPFACHGLHPPPRQGRGSFSREELTGYLLRASAICSKLGLAFLHTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGDAGPPGAPVPSTPAPHASCGSEENHSYTLSLEPETGCQLRHAWTQTESPHPSWETDTVPCPVMDPPSTASSKLDS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites