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MIRAGE
Cadherin-1
Summary
- UniProt ID
- Q90Z37
- Gene Symbol
- cdh1 E-cad
- Gene ID
- 114424
- Organism
- Danio rerio (zebrafish)
External Links
- Re-Glyco
- Q90Z37
Annotation
- Keyword
- Calcium Cell adhesion Cell junction Cell membrane Cytoplasm Endosome Glycoprotein Golgi apparatus Metal-binding Phosphoprotein Reference proteome Repeat Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| cell morphogenesis | ||
| gastrulation with mouth forming second | ||
| neuron migration | ||
| neuron migration | ||
| neural tube formation |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| G-protein alpha-subunit binding | ||
| calcium ion binding | ||
| beta-catenin binding | ||
| cadherin binding |
GO Hierarchy
Sequence
MACVTTVGLGVIFFLFRVFSSGYTHMSICTPGFELEEFVFKVHRNHLHSGKRLGKVTFNNCDGRTRTLFQSIDKRFEINTDGTVTLKRQVTLHEGHKVFSVHAWDSSGMKHTASVRVERVPAQVESSSDVDLTKNKRVKRGWIIPPISVSENSKGPFPMRLVQIKSDYAIETRLAYKITGEGADLDPKGIFTIDRLSGWVSVTQLLDREKKASYKLRAHANGVDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQVGVEVAKLPVTDGDEPESTAWSTKYQIIAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVTVNVKDVNEPPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEKKQNITYRIGNDPSDWLNITGSGQIQVKNALDRESSNVKDGKYKALILALDNDVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPVLLSITDKDLPPFAGPFKVEPQGDTSKNWSVFFNETGHFLNIKPQSQLEQGEYKVVLRVADREGESQENIIQASVCDCKGEAFQCTDKQVAGIPLFGVLGVLGGILLLLLLALLLLMFLRRKSNSKKEPLLPEDDVRDNIYYYDEEGGGEDDQDFDLSVLHRGLDNRPEVFRNDVAPTFMPAPQYRPRPANPEEIGTFIDDNLKAADNDPTAPPYDSLLVFDYEGGGSDAGSLSSLNTSSSGNDQDYDFLNEWGPRFKKLADMYGGGED
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 271 |
|
|
||
| 344 |
|
|
||
| 457 |
|
|
||
| 459 |
|
|
||
| 496 |
|
|
||
| 555 |
|
|
||
| 562 |
|
|
||
| 564 |
|
|
||
| 566 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of STAT3 by cadherin engagement | Danio rerio |
| Adherens junctions interactions | Danio rerio |
| Apoptotic cleavage of cell adhesion proteins | Danio rerio |
| Degradation of CDH1 | Danio rerio |
| Degradation of the extracellular matrix | Danio rerio |
| RHO GTPases activate IQGAPs | Danio rerio |
| Regulation of CDH1 Function | Danio rerio |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | Danio rerio |
| SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST) | Danio rerio |
