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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Heparan-sulfate 6-O-sulfotransferase 2
Summary
- UniProt ID
- Q96MM7
- Gene Symbol
-
- HS6ST2
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0012496
- GlyGen
- Q96MM7
- The Human Metabolome Database
- HMDBP03073
- The O-GlcNAc Database
- Q96MM7
- O-GlcNAcAtlas
- Q96MM7
Annotation
- Keyword
-
- Alternative splicing
- Disease variant
- Glycoprotein
- Intellectual disability
- Reference proteome
- Signal-anchor
- Transferase
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| heparan sulfate proteoglycan biosynthetic process, enzymatic modification |
| GO Term |
|---|
| Golgi membrane |
| GO Term |
|---|
| heparan sulfate 6-O-sulfotransferase activity |
Sequence
MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHGFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLAALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTNDYIGSVEKWR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 183 |
|
|||
| 209 | N-linked (GlcNAc...) asparagine | |||
| 398 |
|
|||
| 404 | N-linked (GlcNAc...) asparagine | |||
| 460 | N-linked (GlcNAc...) asparagine | |||
| 522 |
|
|||
| 528 |
|
|||
| 544 | N-linked (GlcNAc...) asparagine |
|
||
| 556 | N-linked (GlcNAc...) asparagine |
|
||
| 564 | N-linked (GlcNAc...) asparagine |
|
G57321FI
G80920RR
G49108TO
G62765YT
G11314AS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| HS-GAG biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:10534 | stomach cancer | |
| DOID:1059 | intellectual disability | |
| DOID:11830 | myopia | |
| DOID:1324 | lung cancer | |
| DOID:2797 | idiopathic interstitial pneumonia | |
| DOID:381 | arthropathy | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:5517 | stomach carcinoma | |
| DOID:8398 | osteoarthritis |
