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Transferrin receptor protein 1

Summary

UniProt ID

Q99376

Gene Symbol

Tfrc
Trfr

Gene ID

64678

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: Q99376
Re-Glyco: Q99376

Annotation

Keyword

Cell membrane
Disulfide bond
Endocytosis
Glycoprotein
Palmitate
Phosphoprotein
Receptor
Reference proteome
Signal-anchor
Transmembrane helix

Gene Ontology (GO)

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GO Term
clathrin-coated pit
endosome membrane
recycling endosome
recycling endosome membrane
extracellular exosome
glutamatergic synapse
extracellular region
extracellular space
plasma membrane
membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
response to hypoxia
positive regulation of gene expression
osteoclast differentiation
positive regulation of B cell proliferation
intracellular signal transduction
positive regulation of T cell proliferation
negative regulation of apoptotic process
positive regulation of bone resorption
positive regulation of isotype switching
iron ion transport

Displaying **all 8** entries
GO Term
double-stranded RNA binding
transferrin receptor activity
protein kinase binding
Hsp70 protein binding
identical protein binding
protein homodimerization activity
protein-containing complex binding
protein-folding chaperone binding

Annotation information from UniProt.

Sequence

MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAADEEENADSNMKASVRKPKRFNGRLCFATIAVVIFFLIGFMIGYLGYCKRVEQKEECVRLAEAEEADKSENDETEYVPKSSRLFWADLKTLLSEKLNSIEFTDIIKQLSQNTYTPREAGSQKDENLAYYIENLFHDFKFSKVWRDEHYVKIQVKNSVSQNLVTINSGSNIDPVEAPEGYVAFSKAGEVTGKLVHANFGTKKDFEELNYSVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRNTFPVVEADLQFFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAAAEKLFKNMEGNCPPSWNIDSSCKLELSQNQNVKLTVNNVLKETRILNIFGVIKGYEEPDRYIVVGAQRDAWGPGVAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDYGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPIDGKYLYRDSNWISKIEELSLDNAAFPFLAYSGIPAVSFCFCEDEDYPYLGTKLDTYEILIQKVPQLNQMVRTAAEVAGQFIIKLTHDIELTLDYEMYNSKLLSFMKDLNQFKADIKDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLRLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
248	N-linked (GlcNAc...) asparagine	UniProt
252	N-linked (GlcNAc...) asparagine	UniProt
318	N-linked (GlcNAc...) asparagine	UniProt
723	N-linked (GlcNAc...) asparagine	UniProt
728	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Rattus norvegicus
Clathrin-mediated endocytosis	Rattus norvegicus
Golgi Associated Vesicle Biogenesis	Rattus norvegicus
RAC1 GTPase cycle	Rattus norvegicus
RAC2 GTPase cycle	Rattus norvegicus
RHOA GTPase cycle	Rattus norvegicus
RHOB GTPase cycle	Rattus norvegicus
RHOG GTPase cycle	Rattus norvegicus
RHOH GTPase cycle	Rattus norvegicus
RHOQ GTPase cycle	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements