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Endothelial PAS domain-containing protein 1

Summary

UniProt ID

Q99814

Gene Symbol

EPAS1
BHLHE73
HIF2A
MOP2
PASD2

Organism

Homo sapiens (human)

External Links

GlyGen: Q99814
PubChem: Q99814
The O-GlcNAc Database: Q99814

Annotation

Keyword

3D-structure
Activator
Angiogenesis
Congenital erythrocytosis
DNA-binding
Developmental protein
Differentiation
Disease variant
Host-virus interaction
Hydroxylation
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **11 - 20** of 22 in total

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GO Term
lung development
norepinephrine metabolic process
multicellular organismal-level iron ion homeostasis
cellular response to hypoxia
regulation of protein neddylation
mRNA transcription by RNA polymerase II
response to hypoxia
regulation of transcription by RNA polymerase II
mitochondrion organization
positive regulation of transcription by RNA polymerase II

Displaying **all 5** entries
GO Term
chromatin
nuclear speck
cytosol
nucleoplasm
transcription regulator complex

Displaying **all 7** entries
GO Term
RNA polymerase II-specific DNA-binding transcription factor binding
protein heterodimerization activity
RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
RNA polymerase II cis-regulatory region sequence-specific DNA binding
transcription coactivator binding

Annotation information from UniProt.

Sequence

MTADKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGSGFGKKSKDMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVYNNCPPHNSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAMNSIFDSSGKGAVSEKSNFLFTKLKEEPEELAQLAPTPGDAIISLDFGNQNFEESSAYGKAILPPSQPWATELRSHSTQSEAGSLPAFTVPQAAAPGSTTPSATSSSSSCSTPNSPEDYYTSLDNDLKIEVIEKLFAMDTEAKDQCSTQTDFNELDLETLAPYIPMDGEDFQLSPICPEERLLAENPQSTPQHCFSAMTNIFQPLAPVAPHSPFLLDKFQQQLESKKTEPEHRPMSSIFFDAGSKASLPPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQRTEFLGAAPLGPPVSPPHVSTFKTRSAKGFGARGPDVLSPAMVALSNKLKLKRQLEYEEQAFQDLSGGDPPGGSTSHLMWKRMKNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLRHLPLPQPPSAISPGENSKSRFPPQCYATQYQDYSLSSAHKVSGMASRLLGPSFESYLLPELTRYDCEVNVPVLGSSTLLQGGDLLRALDQAT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Cellular response to hypoxia	Homo sapiens
Neddylation	Homo sapiens
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	Homo sapiens
PTK6 Expression	Homo sapiens
Pexophagy	Homo sapiens
Regulation of gene expression by Hypoxia-inducible Factor	Homo sapiens
Transcriptional regulation of pluripotent stem cells	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements