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Toll-like receptor 3

Summary

UniProt ID

Q99MB1

Gene Symbol

Tlr3

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007250
GlyGen: Q99MB1
PubChem: Q99MB1

Annotation

Keyword

3D-structure
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Isopeptide bond
Leucine-rich repeat
Phosphoprotein
RNA-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 42 in total

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GO Term
cellular response to interferon-beta
microglial cell activation
regulation of dendritic cell cytokine production
defense response
inflammatory response
male gonad development
innate immune response
positive regulation of angiogenesis
inflammatory response to wounding
positive regulation of type I interferon production

Displaying **all 5** entries
GO Term
plasma membrane
endoplasmic reticulum membrane
endosome membrane
early endosome
cell surface

Displaying **all 5** entries
GO Term
identical protein binding
double-stranded RNA binding
transmembrane signaling receptor activity
signaling receptor activity
pattern recognition receptor activity

Annotation information from UniProt.

Sequence

MKGCSSYLMYSFGGLLSLWILLVSSTNQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQKNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSSNPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSESTFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYLSLKRAFTKQSVSLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSLSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQKLSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLRNLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLHILNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEKDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGFPLKLFDTSSCKDSAPFELLFIISTSMLLVFILVVLLIHIEGWRISFYWNVSVHRILGFKEIDTQAEQFEYTAYIIHAHKDRDWVWEHFSPMEEQDQSLKFCLEERDFEAGVLGLEAIVNSIKRSRKIIFVITHHLLKDPLCRRFKVHHAVQQAIEQNLDSIILIFLQNIPDYKLNHALCLRRGMFKSHCILNWPVQKERINAFHHKLQVALGSRNSAH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 15 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
53	N-linked (GlcNAc...) asparagine		G82390KS	GlycoProtDB UniProt GlyGen
58	N-linked (GlcNAc...) asparagine		G94345WB	GlycoProtDB UniProt GlyGen
71	N-linked (GlcNAc...) asparagine	18420935	G92275SC	UniProt GlyGen
125	N-linked (GlcNAc...) asparagine			UniProt GlyGen
197	N-linked (GlcNAc...) asparagine	18420935	G92275SC	GlycoProtDB UniProt GlyGen
248	N-linked (GlcNAc...) asparagine			UniProt GlyGen
253	N-linked (GlcNAc...) asparagine	18420935		UniProt GlyGen
276	N-linked (GlcNAc...) asparagine	18420935	G07246CJ	GlycoProtDB UniProt GlyGen
292	N-linked (GlcNAc...) asparagine	18420935		GlycoProtDB UniProt GlyGen
399	N-linked (GlcNAc...) asparagine	18420935	G07036HW	GlycoProtDB UniProt GlyGen