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Toll-like receptor 3

Summary

UniProt ID

Q99MB1

Gene Symbol

Tlr3

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007250
GlyGen: Q99MB1
PubChem: Q99MB1

Annotation

Keyword

3D-structure
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Isopeptide bond
Leucine-rich repeat
Phosphoprotein
RNA-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 42 in total

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GO Term
microglial cell activation
regulation of dendritic cell cytokine production
defense response
positive regulation of apoptotic process
positive regulation of macrophage cytokine production
positive regulation of cytokine production involved in inflammatory response
cellular response to type II interferon
response to exogenous dsRNA
response to dsRNA
positive regulation of JNK cascade

Displaying **all 5** entries
GO Term
endoplasmic reticulum membrane
endosome membrane
early endosome
cell surface
plasma membrane

Displaying **all 5** entries
GO Term
identical protein binding
double-stranded RNA binding
transmembrane signaling receptor activity
signaling receptor activity
pattern recognition receptor activity

Annotation information from UniProt.

Sequence

MKGCSSYLMYSFGGLLSLWILLVSSTNQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQKNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSSNPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSESTFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYLSLKRAFTKQSVSLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSLSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQKLSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLRNLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLHILNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEKDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGFPLKLFDTSSCKDSAPFELLFIISTSMLLVFILVVLLIHIEGWRISFYWNVSVHRILGFKEIDTQAEQFEYTAYIIHAHKDRDWVWEHFSPMEEQDQSLKFCLEERDFEAGVLGLEAIVNSIKRSRKIIFVITHHLLKDPLCRRFKVHHAVQQAIEQNLDSIILIFLQNIPDYKLNHALCLRRGMFKSHCILNWPVQKERINAFHHKLQVALGSRNSAH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 15** of 15 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
414	N-linked (GlcNAc...) asparagine	18420935		GlycoProtDB UniProt GlyGen
425	N-linked (GlcNAc...) asparagine	18420935	G80920RR	GlycoProtDB UniProt GlyGen
508	N-linked (GlcNAc...) asparagine	18420935		UniProt GlyGen
663	N-linked (GlcNAc...) asparagine	18420935		UniProt GlyGen
668	N-linked (GlcNAc...) asparagine	18420935		UniProt GlyGen