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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Frizzled-8
Summary
- UniProt ID
- Q9H461
- Gene Symbol
-
- FZD8
- Organism
- Homo sapiens (human)
External Links
- PubChem
- Q9H461
- The Human Metabolome Database
- HMDBP07704
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Developmental protein
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Golgi apparatus
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| Wnt-Frizzled-LRP5/6 complex |
| neuronal dense core vesicle |
| Golgi apparatus |
| plasma membrane |
| membrane |
| GO Term |
|---|
| G protein-coupled receptor activity |
| signaling receptor binding |
| Wnt-protein binding |
| PDZ domain binding |
| ubiquitin protein ligase binding |
| Wnt receptor activity |
Sequence
MEWGYLLEVTSLLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGSGHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESWRSLCTRCCWASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGGGGSLYSDVSTGLTWRSGTASSVSYPKQMPLSQV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Asymmetric localization of PCP proteins | Homo sapiens |
| Class B/2 (Secretin family receptors) | Homo sapiens |
| Regulation of FZD by ubiquitination | Homo sapiens |
| Signaling by RNF43 mutants | Homo sapiens |
