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DNA mismatch repair protein Mlh1
Summary
- UniProt ID
- Q9JK91
- Gene Symbol
-
- Mlh1
- Gene ID
- 17350
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Cell cycle
- Chromosome
- DNA repair
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| nucleoplasm |
| condensed chromosome |
| synaptonemal complex |
| chiasma |
| late recombination nodule |
| MutLalpha complex |
| male germ cell nucleus |
| condensed nuclear chromosome |
| chromosome |
Sequence
MAFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTNIQVVVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRRKALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCEDKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESAALRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILQRVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEAARPTTGVASSSTSGSGDKVYAYQMVRTDSREQKLDAFLQPVSSLGPSQPQDPAPVRGARTEGSPERATREDEEMLALPAPAEAAAESENLERESLMETSDAAQKAAPTSSPGSSRKRHREDSDVEMVENASGKEMTAACYPRRRIINLTSVLSLQEEISERCHETLREMLRNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEDDGPKEGLAEYIVEFLKKKAEMLADYFSVEIDEEGNLIGLPLLIDSYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYILEESTLSGQQSDMPGSTSKPWKWTVEHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLYKVFERC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 64 |
|
G72735IY
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3883 | Lynch syndrome |
