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MIRAGE
Frizzled-4
Summary
- UniProt ID
- Q9ULV1
- Gene Symbol
-
- FZD4
- Gene ID
- 8322
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- Q9ULV1
- PubChem
- Q9ULV1
- The Human Metabolome Database
- HMDBP07700
- Re-Glyco
- Q9ULV1
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Developmental protein
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| clathrin-coated endocytic vesicle membrane |
| cell-cell junction |
| dendrite |
| cell surface |
| plasma membrane |
| glutamatergic synapse |
Sequence
MAWRGAGPSVPGAPGGVGLSLGLLLQLLLLLGPARGFGDEEERRCDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNGWVKPGKGSETVV
Glycosylation Sites
G83460ZZ
G51413EV
G22310AV
G45395BF
G40574BA
G75983OB
G48414YA
G84452RH
G63041LO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Asymmetric localization of PCP proteins | Homo sapiens |
| Ca2+ pathway | Homo sapiens |
| Cargo recognition for clathrin-mediated endocytosis | Homo sapiens |
| Class B/2 (Secretin family receptors) | Homo sapiens |
| Clathrin-mediated endocytosis | Homo sapiens |
| Regulation of FZD by ubiquitination | Homo sapiens |
| Signaling by RNF43 mutants | Homo sapiens |
| WNT5A-dependent internalization of FZD4 | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111412 | exudative vitreoretinopathy 1 |
