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Frizzled-4

Summary

UniProt ID

Q9ULV1

Gene Symbol

FZD4

Organism

Homo sapiens (human)

External Links

GlyConnect

2003

GlyGen

Q9ULV1

PubChem

Q9ULV1

The Human Metabolome Database

HMDBP07700

Annotation

Keyword

3D-structure
Cell membrane
Developmental protein
Disease variant
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Transmembrane helix
Ubl conjugation
Wnt signaling pathway

Gene Ontology (GO)

Displaying entries **1 - 10** of 29 in total

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GO Term
angiogenesis
vasculogenesis
sensory perception of sound
cell population proliferation
neuron differentiation
positive regulation of cell migration
progesterone secretion
endothelial cell differentiation
locomotion involved in locomotory behavior
positive regulation of dendrite morphogenesis

Displaying **all 6** entries
GO Term
plasma membrane
cell-cell junction
dendrite
glutamatergic synapse
clathrin-coated endocytic vesicle membrane
cell surface

Displaying entries **1 - 10** of 12 in total

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GO Term
cytokine receptor activity
G protein-coupled receptor activity
cytokine binding
signaling receptor activity
protein-containing complex binding
Wnt-protein binding
PDZ domain binding
ubiquitin protein ligase binding
protein homodimerization activity
Wnt receptor activity

Annotation information from UniProt.

Sequence

MAWRGAGPSVPGAPGGVGLSLGLLLQLLLLLGPARGFGDEEERRCDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNGWVKPGKGSETVV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
59	N-linked (GlcNAc...) asparagine		G83460ZZ	UniProt GlyGen
144	N-linked (GlcNAc...) asparagine		G51413EV G22310AV G45395BF G40574BA G75983OB G48414YA G84452RH G63041LO G29879MS	UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Asymmetric localization of PCP proteins	Homo sapiens
Ca2+ pathway	Homo sapiens
Cargo recognition for clathrin-mediated endocytosis	Homo sapiens
Class B/2 (Secretin family receptors)	Homo sapiens
Clathrin-mediated endocytosis	Homo sapiens
Regulation of FZD by ubiquitination	Homo sapiens
Signaling by RNF43 mutants	Homo sapiens
WNT5A-dependent internalization of FZD4	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements