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Sterol regulatory element-binding protein 1

Summary

UniProt ID

Q9WTN3

Gene Symbol

Srebf1
Srebp1

Gene ID

20787

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9WTN3
PubChem: Q9WTN3
O-GlcNAcAtlas: Q9WTN3
Re-Glyco: Q9WTN3

Annotation

Keyword

Activator
Alternative splicing
Cholesterol metabolism
Cytoplasmic vesicle
DNA-binding
Endoplasmic reticulum
Golgi apparatus
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
nucleus
cytoplasm
membrane
protein-containing complex
Golgi membrane
nucleoplasm
endoplasmic reticulum membrane
ER to Golgi transport vesicle membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 42 in total

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GO Term
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
regulation of heart rate by chemical signal
circadian rhythm
lipid biosynthetic process
regulation of fatty acid metabolic process
insulin secretion
lung development
positive regulation of innate immune response
negative regulation of insulin secretion

Displaying entries **1 - 10** of 14 in total

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GO Term
protein kinase binding
sequence-specific DNA binding
protein-containing complex binding
protein dimerization activity
transcription cis-regulatory region binding
chromatin binding
nuclear receptor activity
sterol response element binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific

Annotation information from UniProt.

Sequence

MDELAFGEAALEQTLAEMCELDTAVLNDIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPSSPGANSPESFSSASLASSLEAFLGGPKVTPAPLSPPPSAPAALKMYPSVSPFSPGPGIKEEPVPLTILQPAAPQPSPGTLLPPSFPAPPVQLSPAPVLGYSSLPSGFSGTLPGNTQQPPSSLPLAPAPGVLPTPALHTQVQSLASQQPLPASAAPRTNTVTSQVQQVPVVLQPHFIKADSLLLTAVKTDAGATVKTAGISTLAPGTAVQAGPLQTLVSGGTILATVPLVVDTDKLPIHRLAAGSKALGSAQSRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLTLRSAHKSKSLKDLVSACGSGGGTDVSMEGMKPEVVETLTPPPSDAGSPSQSSPLSFGSRASSSGGSDSEPDSPAFEDSQVKAQRLPSHSRGMLDRSRLALCVLAFLCLTCNPLASLFGWGILTPSDATGTHRSSGRSMLEAESRDGSNWTQWLLPPLVWLANGLLVLACLALLFVYGEPVTRPHSGPAVHFWRHRKQADLDLARGDFPQAAQQLWLALQALGRPLPTSNLDLACSLLWNLIRHLLQRLWVGRWLAGQAGGLLRDRGLRKDARASARDAAVVYHKLHQLHAMGKYTGGHLAASNLALSALNLAECAGDAISMATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPLAMQWLCHPVGHRFFVDGDWAVHGAPPESLYSVAGNPVDPLAQVTRLFREHLLERALNCIAQPSPGAADGDREFSDALGYLQLLNSCSDAAGAPACSFSVSSSMAATTGPDPVAKWWASLTAVVIHWLRRDEEAAERLYPLVEHIPQVLQDTERPLPRAALYSFKAARALLDHRKVESSPASLAICEKASGYLRDSLASTPTGSSIDKAMQLLLCDLLLVARTSLWQRQQSPASVQVAHGTSNGPQASALELRGFQHDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPARTHQLLDRSLRRRAGSSGKGGTTAELEPRPTWREHTEALLLASCYLPPAFLSAPGQRMSMLAEAARTVEKLGDHRLLLDCQQMLLRLGGGTTVTSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites