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Sterol regulatory element-binding protein 1

Summary

UniProt ID

Q9WTN3

Gene Symbol

Srebf1
Srebp1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9WTN3
PubChem: Q9WTN3
O-GlcNAcAtlas: Q9WTN3

Annotation

Keyword

Activator
Alternative splicing
Cholesterol metabolism
Cytoplasmic vesicle
DNA-binding
Endoplasmic reticulum
Golgi apparatus
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 43 in total

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GO Term
regulation of DNA-templated transcription
positive regulation of miRNA transcription
transcription by RNA polymerase II
response to glucose
response to food
SREBP signaling pathway
fat cell differentiation
positive regulation of cholesterol biosynthetic process
response to cAMP
cellular response to fatty acid

Displaying **all 8** entries
GO Term
nucleus
cytoplasm
membrane
protein-containing complex
ER to Golgi transport vesicle membrane
Golgi membrane
nucleoplasm
endoplasmic reticulum membrane

Displaying entries **1 - 10** of 13 in total

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GO Term
chromatin binding
sterol response element binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
transcription coregulator binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
DNA-binding transcription factor activity
protein kinase binding
sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MDELAFGEAALEQTLAEMCELDTAVLNDIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPSSPGANSPESFSSASLASSLEAFLGGPKVTPAPLSPPPSAPAALKMYPSVSPFSPGPGIKEEPVPLTILQPAAPQPSPGTLLPPSFPAPPVQLSPAPVLGYSSLPSGFSGTLPGNTQQPPSSLPLAPAPGVLPTPALHTQVQSLASQQPLPASAAPRTNTVTSQVQQVPVVLQPHFIKADSLLLTAVKTDAGATVKTAGISTLAPGTAVQAGPLQTLVSGGTILATVPLVVDTDKLPIHRLAAGSKALGSAQSRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLTLRSAHKSKSLKDLVSACGSGGGTDVSMEGMKPEVVETLTPPPSDAGSPSQSSPLSFGSRASSSGGSDSEPDSPAFEDSQVKAQRLPSHSRGMLDRSRLALCVLAFLCLTCNPLASLFGWGILTPSDATGTHRSSGRSMLEAESRDGSNWTQWLLPPLVWLANGLLVLACLALLFVYGEPVTRPHSGPAVHFWRHRKQADLDLARGDFPQAAQQLWLALQALGRPLPTSNLDLACSLLWNLIRHLLQRLWVGRWLAGQAGGLLRDRGLRKDARASARDAAVVYHKLHQLHAMGKYTGGHLAASNLALSALNLAECAGDAISMATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPLAMQWLCHPVGHRFFVDGDWAVHGAPPESLYSVAGNPVDPLAQVTRLFREHLLERALNCIAQPSPGAADGDREFSDALGYLQLLNSCSDAAGAPACSFSVSSSMAATTGPDPVAKWWASLTAVVIHWLRRDEEAAERLYPLVEHIPQVLQDTERPLPRAALYSFKAARALLDHRKVESSPASLAICEKASGYLRDSLASTPTGSSIDKAMQLLLCDLLLVARTSLWQRQQSPASVQVAHGTSNGPQASALELRGFQHDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPARTHQLLDRSLRRRAGSSGKGGTTAELEPRPTWREHTEALLLASCYLPPAFLSAPGQRMSMLAEAARTVEKLGDHRLLLDCQQMLLRLGGGTTVTSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites