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Sterol regulatory element-binding protein 1

Summary

UniProt ID

Q9WTN3

Gene Symbol

Srebf1
Srebp1

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q9WTN3
PubChem: Q9WTN3
O-GlcNAcAtlas: Q9WTN3
Re-Glyco: Q9WTN3

Annotation

Keyword

Activator
Alternative splicing
Cholesterol metabolism
Cytoplasmic vesicle
DNA-binding
Endoplasmic reticulum
Golgi apparatus
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
Golgi membrane
nucleoplasm
endoplasmic reticulum membrane
nucleus
cytoplasm
membrane
protein-containing complex
ER to Golgi transport vesicle membrane

Displaying entries **11 - 20** of 43 in total

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GO Term
positive regulation of lipid biosynthetic process
regulation of insulin secretion
regulation of heart rate by chemical signal
response to fructose
positive regulation of triglyceride biosynthetic process
response to glucagon
positive regulation of fatty acid biosynthetic process
negative regulation of triglyceride metabolic process
regulation of mitophagy
negative regulation of transcription by RNA polymerase II

Displaying entries **1 - 10** of 13 in total

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GO Term
nuclear receptor activity
chromatin binding
sterol response element binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
transcription coregulator binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
DNA-binding transcription factor activity
protein kinase binding

Annotation information from UniProt.

Sequence

MDELAFGEAALEQTLAEMCELDTAVLNDIEDMLQLINNQDSDFPGLFDAPYAGGETGDTGPSSPGANSPESFSSASLASSLEAFLGGPKVTPAPLSPPPSAPAALKMYPSVSPFSPGPGIKEEPVPLTILQPAAPQPSPGTLLPPSFPAPPVQLSPAPVLGYSSLPSGFSGTLPGNTQQPPSSLPLAPAPGVLPTPALHTQVQSLASQQPLPASAAPRTNTVTSQVQQVPVVLQPHFIKADSLLLTAVKTDAGATVKTAGISTLAPGTAVQAGPLQTLVSGGTILATVPLVVDTDKLPIHRLAAGSKALGSAQSRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLTLRSAHKSKSLKDLVSACGSGGGTDVSMEGMKPEVVETLTPPPSDAGSPSQSSPLSFGSRASSSGGSDSEPDSPAFEDSQVKAQRLPSHSRGMLDRSRLALCVLAFLCLTCNPLASLFGWGILTPSDATGTHRSSGRSMLEAESRDGSNWTQWLLPPLVWLANGLLVLACLALLFVYGEPVTRPHSGPAVHFWRHRKQADLDLARGDFPQAAQQLWLALQALGRPLPTSNLDLACSLLWNLIRHLLQRLWVGRWLAGQAGGLLRDRGLRKDARASARDAAVVYHKLHQLHAMGKYTGGHLAASNLALSALNLAECAGDAISMATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPLAMQWLCHPVGHRFFVDGDWAVHGAPPESLYSVAGNPVDPLAQVTRLFREHLLERALNCIAQPSPGAADGDREFSDALGYLQLLNSCSDAAGAPACSFSVSSSMAATTGPDPVAKWWASLTAVVIHWLRRDEEAAERLYPLVEHIPQVLQDTERPLPRAALYSFKAARALLDHRKVESSPASLAICEKASGYLRDSLASTPTGSSIDKAMQLLLCDLLLVARTSLWQRQQSPASVQVAHGTSNGPQASALELRGFQHDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPARTHQLLDRSLRRRAGSSGKGGTTAELEPRPTWREHTEALLLASCYLPPAFLSAPGQRMSMLAEAARTVEKLGDHRLLLDCQQMLLRLGGGTTVTSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites